Publications by authors named "Bjoern Gisk"
Heme oxygenases (HO) degrade heme yielding iron, carbon monoxide and one of four possible biliverdin (BV) isomers. Pseudomonas aeruginosa PAO1 is thus far the only organism to contain two HOs with different regiospecificities: BphO and PigA. While BphO cleaves heme to exclusively yield BV IXα, PigA produces the BV isomers IXβ and IXδ.
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- HOs (haem oxygenases) break down haem into biliverdin (BV), iron, and carbon monoxide, with BV IXalpha being crucial for plant light responses and growth.
- In the model plant Arabidopsis thaliana, there are four HO proteins (HY1, HO2, HO3, HO4), which can be grouped into two subfamilies, with the first group (HO1) actively converting haem to BV IXalpha using electron donors like spinach ferredoxin and ascorbate.
- While HO2 cannot degrade haem and doesn't function as a typical HO, it strongly binds to protoporphyrin IX, suggesting it may play a regulatory role in the metabolism of other important pigments like