A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells.

Cancer is the most acute disease and the leading cause of patient death worldwide. Both chemotherapy and molecular-based therapies play an important role in curing cancer. However, the median and overall survival of patients is poor.

Exergy Analysis of Phase-Change Heat-Storage Coupled Solar Heat Pump Heating System.

With the rapid development of industrialization, the excessive use of fossil fuels has caused problems such as increased greenhouse gas emissions and energy shortages. The development and use of renewable energy has attracted increased attention. In recent years, solar heat pump heating technology that uses clean solar energy combined with high-efficiency heat pump units is the development direction of clean heating in winter in northern regions.

Flexible ferroelasticity in monolayer PdS: a DFT study.

As an unusual mechanical response, the ferroelastic phenomenon in two-dimensional materials has been reported both experimentally and theoretically in recent years. Here, we present the theoretical findings of ferroelastic switching in monolayer PdS2. We demonstrate four types of PdS2 allotropes, showing excellent ferroelasticity with low ferroelastic barriers and strong switching signals.

SO Electrocatalytic Oxidation Properties of Pt-Ru/C Bimetallic Catalysts with Different Nanostructures.

Electrocatalytic oxidation of SO has been applied in many fields, and electrocatalyst is the focus of the research. Platinum-based electrocatalysts are the hot spot in this reaction. Although the properties of these materials have been optimized to a certain extent, there is still room for improvement in activity and long-term durability.

High-Performance Pt Catalyst with Graphene/Carbon Black as a Hybrid Support for SO Electrocatalytic Oxidation.

In the electrochemical Bunsen reaction, which is the key reaction of the sulfur-iodide cycle, the main overpotential corresponds to the oxidation of SO. The catalysts currently used for the liquid phase electrocatalytic oxidation of SO are mainly based on noble metals, which have excellent corrosion resistance and catalytic activity in an acidic environment. To improve the performance of the commercial Pt catalyst, a Pt catalyst with reduced graphene oxide (RGO) and carbon black as a hybrid support was synthesized by the microwave-assisted polyol reduction process.

Treatment of type 2 diabetes mellitus in a primary care setting in Taiwan: comparison with secondary/tertiary care.

Background: This study investigated the status of diabetes control and management in patients treated in a primary healthcare setting and compared the results with data previously obtained for secondary/tertiary care patients in Taiwan.

Methods: This study was conducted at 51 primary healthcare stations randomly selected island-wide in Taiwan in 2001. A total of 1302 type 2 diabetes patients who had been followed-up for more than 1 year were included.