Synthesis of copper hexaferrite magnetic nanoparticles based on carboxymethyl cellulose modified with polyacrylic acid (CMC/PAA/CuFeO) for loading and release of Levothyroxine.

Hypothyroidism is a disease that is treated using levothyroxine sodium orally, and its oral use causes some problems in its absorption. A potential alternative to improve its administration is the use of drug delivery systems. This research aimed to prepare CMC/PAA/CuFeO magnetic nano polymer and investigate its performance in the loading and release of Levothyroxine.