Lupus glomerulonephritis: a clinicopathological correlation of 93 patients of systemic lupus erythematosus for a follow-up period of three years.

A prospective study of 93 patients (female 86, male 7) of systemic lupus erythematosus (SLE) attending NRS Medical College and Hospital was done with special reference to their renal affection. Clinical features were noted and various laboratory parameters including auto-antibodies (ANF, anti ds DNA) were performed. Histopathological study of renal biopsy was carried out both at the time of presentation and subsequently 1 and 3 years later and lupus glomerulonephritis (LN) was categorised according to World Health Organisation (WHO) classification.

Homocysteine and cerebrovascular accidents.

Hyperhomocysteinaemia is rapidly emerging as an important risk factor for coronary artery disease, possibly because of its propensity to accelerate atherosclerosis. Whether it is also a risk factor for cerebrovascular accidents (CVA) is a matter of debate till now, as there are conflicting results of the various prospective studies. The present study was performed to correlate the levels of plasma homocysteine levels with that of ischaemic and haemorrhagic CVA.

Hepatitis C--clinical profile.

Hepatitis C virus is a small enveloped RNA virus of the flaviviridae family of genus hepacivirus. Hepatitis C is one of the five viruses that account for majority of cases of viral hepatitis. Hepatitis C has a variable course that can lead to chronic hepatitis, cirrhosis and hepatocellular carcinoma.