Background: The genomic landscape of non-small cell lung cancer (NSCLC) in the Indian patients remains underexplored. We revealed distinctive genomic alterations of Indian NSCLC patients, thereby providing vital molecular insights for implementation of precision therapies.
Methods: We analyzed the genomic profiles of 325 lung adenocarcinoma and 81 lung squamous carcinoma samples from Indian patients using targeted sequencing of 50 cancer related genes.
Background: Neoadjuvant chemoradiotherapy (NACRT) using CROSS protocol is currently the treatment of choice for esophageal cancer (EC). Tumor response grade (TRG) is a mandatory reporting criterion in most guidelines. One of the most commonly used TRG systems is the modified Ryan system.
View Article and Find Full Text PDFIndian J Dermatol Venereol Leprol
April 2024
Pseudoaneurysms are a commonly encountered pathology, though pseudoaneurysms of the visceral arteries are a less frequent, but potentially deadly entity. Transarterial embolization is the typical treatment of visceral pseudoaneurysms, but success is dependent on anatomy that is conducive to selecting the supplying vessel. Abdominal ultrasound is a viable method to effectively treat visceral pseudoaneurysms when transarterial embolization is not possible.
View Article and Find Full Text PDFThe Sustainable Development Goals (SDGs) are a global appeal to protect the environment, combat climate change, eradicate poverty, and ensure access to a high quality of life and prosperity for all. The next decade is crucial for determining the planet's direction in ensuring that populations can adapt to climate change. This study aims to investigate the progress, challenges, opportunities, trends, and prospects of the SDGs through a bibliometric analysis from 2015 to 2022, providing insight into the evolution and maturity of scientific research in the field.
View Article and Find Full Text PDFIn this paper, we use the analytical lens of social wellbeing to interpret the history of livelihood change in the coastal village of Saiyad Rajpara in Gujarat over the past 70 years. We describe a broad narrative of transition from food scarcity to food security brought about by the introduction and intensification of bag net fishing in the village. This form of fishing has largely displaced the previous economic basis for livelihoods of uncertain daily wage labour.
View Article and Find Full Text PDFAppl Biochem Biotechnol
December 2023
Diabetes-associated postprandial hyperglycemia is a major risk factor in cardiovascular disease. Since enzyme α-glucosidase is primarily responsible for glucose release during digestion, inhibiting it mitigates post-meal spike in blood glucose level. Metabolites from endophytic fungi could be potential natural inhibitors of this enzyme.
View Article and Find Full Text PDFPersons with mental illness have the right to live a life with dignity like others. Despite a separate Mental Healthcare Act (MHC Act, 2017), mental illness is included in the Rights of Persons with Disabilities (RPWD Act, 2016). We present a critical review of the Acts, their associated rules, rights, entitlements, and provisions of care for mental illness for any amendment in case of any discrepancy to ensure clarity in understanding of the rights and provisions of care and their smooth implementation.
View Article and Find Full Text PDFIn Distributed Hash Table (DHT)-based Mobile Ad Hoc Networks (MANETs), a logical structured network (i.e., follows a tree, ring, chord, 3D, etc.
View Article and Find Full Text PDFCyberhate represents a risk to adolescents' development and peaceful coexistence in democratic societies. Yet, not much is known about the relationship between adolescents' ability to cope with cyberhate and their cyberhate involvement. To fill current gaps in the literature and inform the development of media education programs, the present study investigated various coping strategies in a hypothetical cyberhate scenario as correlates for being cyberhate victims, perpetrators, and both victim-perpetrators.
View Article and Find Full Text PDFThe defocus or motion effect in images is one of the main reasons for the blurry regions in digital images. It can affect the image artifacts up to some extent. However, there is a need for automatic defocus segmentation to separate blurred and sharp regions to extract the information about defocus-blur objects in some specific areas, for example, scene enhancement and object detection or recognition in defocus-blur images.
View Article and Find Full Text PDFA UHPLC-QTOF-MS method was developed to separate and identify 70 triterpenes present in each of the 18 strains of Ganoderma spp. Collected from various parts of India. A PCDL MS library was used to retrieve and identify these 70 triterpenes by meticulous analysis of MS/MS fragments.
View Article and Find Full Text PDFThe ever-growing ecosystem of the Internet of Things (IoT) integrating with the ever-evolving wireless communication technology paves the way for adopting new applications in a smart society. The core concept of smart society emphasizes utilizing information and communication technology (ICT) infrastructure to improve every aspect of life. Among the variety of smart services, eHealth is at the forefront of these promises.
View Article and Find Full Text PDFThe authors wish to add the following corrections to their paper published in the International Journal of Environmental Research and Public Health [...
View Article and Find Full Text PDFFunerals are a reflective practice to bid farewell to the departed soul. Different religions, cultural traditions, rituals, and social beliefs guide how funeral practices take place. Family and friends gather together to support each other in times of grief.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
August 2021
Purpose: The ongoing coronavirus disease 19 (COVID-19) pandemic is spreading at an alarming rate across the globe. Sudden onset loss of smell and/or taste has been increasingly reported as a symptom of COVID-19. However, prevalence of these symptoms, and its severity varies widely between studies, with little data on its duration and recovery rate.
View Article and Find Full Text PDFSensors (Basel)
December 2020
Undoped and nickel-doped zinc oxide thin films were deposited on sodalime glass substrates by utilizing dip coating and ultrasonic spray pyrolysis deposition techniques. In both cases zinc acetate and nickel acetylacetonate were used as zinc precursor and nickel dopant source, respectively. XRD analysis confirms the ZnO wurtzite structure with (002) as the preferential orientation.
View Article and Find Full Text PDFComput Intell Neurosci
April 2021
With the growing information on web, online movie review is becoming a significant information resource for Internet users. However, online users post thousands of movie reviews on daily basis and it is hard for them to manually summarize the reviews. Movie review mining and summarization is one of the challenging tasks in natural language processing.
View Article and Find Full Text PDFResearch in mental health is a complex phenomenon that requires the use of more than one technique. It is extremely crucial to study and understand people's perceptions, beliefs, healing practices and coping strategies related to mental health. Stipulating only one between the medical/biomedical and medical anthropology perspectives may not be adequate to understand the dynamics of mental health research.
View Article and Find Full Text PDFLittle attention has been given academically to empirically tested theoretical frameworks that aim at measuring the risk of adolescents falling victim to cybergrooming. To this end, we have applied the routine activity theory (RAT) to investigate whether exposure to motivated offenders (PC/laptop ownership and Internet access in one's own bedroom), capable guardianship (parental mediation strategies of Internet use), and target suitability (adolescents' online disclosure of private information) might predict cybergrooming victimization among adolescents. Using data from a cross-sectional survey of 5,938 adolescents from Germany, India, South Korea, Spain, Thailand, and the United States, ranging in age from 12 to 18 ( = 14.
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