Purpose: Diabetes mellitus is a global health challenge that leads to severe complications, negatively impacting overall health, life expectancy, and quality of life. Herbal medicines, valued for their accessibility and therapeutic benefits with minimal side effects, have been promoted as potential treatments. Managing conditions like diabetes, characterized by free radical production and cytokine-driven inflammation, is vital due to the active components in plants that exert direct pharmacological effects.
View Article and Find Full Text PDFThis study examines the effect of gestational administration of aqueous leaf extract of Jatropha tanjorensis (JT) on postpartum-like behavioural outcomes to delineate its possibility as a prophylactic, therapeutic agent in the treatment of postpartum symptoms. Inseminated female rats (120-150g) were grouped into two-control and JT group (n=10). Control received 20 ml/kg of distilled water and JT group received 500 mg/kg of JT orally once daily for 21 days in gestation.
View Article and Find Full Text PDFIn spite of the overwhelming patronage of the plant Jatropha tanjorensis (J.T) popularly called "Hospital Too Far" by pregnant and women of reproductive age for its supposed reproductive benefits, the scientific evidence are hardly known. This study thus sought to examine the effect of consumption of aqueous leaf of J.
View Article and Find Full Text PDFObjective: Virgin coconut oil (VCO) has been used in the management of dementia in Alzheimer's disease (AD). Therefore, this research investigated the effect of long-term consumption of VCO diet on learning and memory in CD1 mice.
Methods: Thirty male CD1 mice (divided into three groups, = 10) were fed with standard rodent chow (control), 5% and 20% VCO diets (respectively) for 28 d.
Most antipsychotics interfere with the dopaminergic system, resulting in extrapyramidal effects. This study compared the extrapyramidal effects of chlorpromazine (Cpz), the herb Rauwolfia vomitoria (RV) and its alkaloid reserpine (Res), used as antipsychotics, in mice. Ninety age-matched male CD-1 strain of mice (25-33 g body weight) were divided into 3 groups, each consisting of 5 subgroups (n = 6).
View Article and Find Full Text PDFBackground: Rauwolfia vomitoria has been used in Nigeria to manage psychiatric disorders despite orthodox medicine.
Aims: This research was therefore aimed at comparing the effects of R. vomitoria, chlorpromazine and reserpine on social behaviour and pain in mice.
Aim Of The Study: Since remedies for mental disorders have been sought through both orthodox and traditional medicine this study compared the effects of the antipsychotic, chlorpromazine (Cpz), the herb Rauwolfia vomitoria (RV) and its alkaloid reserpine (Res) in mice.
Materials And Methods: Ninety male CD-1 strain of mice (75-80 days old; 30-34 g body weight) were divided into 3 major groups and each consisting 5 subgroups (n=6). Cpz (0.