Bats are recognized as natural reservoirs for an array of diverse viruses, particularly coronaviruses, which have been linked to major human diseases like SARS-CoV and MERS-CoV. These viruses are believed to have originated in bats, highlighting their role in virus ecology and evolution. Our study focuses on the molecular characterization of bat-derived coronaviruses (CoVs) in Canada.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Introduction: Peritoneal hydatid disease accounts for 2-13 % of abdominal hydatidosis cases. Due to its nonspecific clinical presentation and potential for multi-organ involvement, the condition is often misdiagnosed. Evidence on managing primary peritoneal hydatid cysts remains limited, presenting challenges in diagnosis and treatment.
View Article and Find Full Text PDFBiliary stents are widely used following endoscopic management of choledocholithiasis. Removal is recommended within 3-6 months to prevent complications. This study analyzed cases of retained biliary stents managed at our institution.
View Article and Find Full Text PDFBackground Liver transplantation is the standard treatment for end-stage liver disease. Living donor liver transplantation is more commonly performed in Asian countries as compared to the Western due to the lack of organ donation. Donor safety is the key to sustaining a liver transplant program.
View Article and Find Full Text PDFIntroduction The prognostic significance of the controlling nutritional status (CONUT) score in hepatopancreatobiliary (HPB) surgery has been shown by many studies but the clinical significance of the CONUT score for postoperative short-term outcomes remains controversial. This study aimed to investigate the impact of the CONUT score on early postoperative outcomes in patients following major HPB surgery. Method This was a prospective study of 57 patients who underwent major HPB surgery from November 2019 to January 2021 at the Department of Surgical Gastroenterology, Tribhuvan University Teaching Hospital, Nepal.
View Article and Find Full Text PDFIntroduction And Importance: Acute appendicitis is a common surgical emergency marked by appendix inflammation, presenting as acute abdominal pain and typically treated with appendectomy. The authors report a rare case of disseminated appendicular lymphoma presenting as acute appendicitis. Acute appendicitis is a common surgical emergency.
View Article and Find Full Text PDFIntroduction Systematic mesopancreas dissection (SMD) is an emerging surgical approach in pancreatic cancer surgery. There is still debate about early postoperative and pathological outcomes using SMD in pancreatic cancer surgery. This study has been conducted to compare the perioperative outcomes, the lymph node yield, and the margin status in patients who underwent standard pancreaticoduodenectomy (ST-PD) and SMD-PD for pancreatic and periampullary carcinoma.
View Article and Find Full Text PDFUnlabelled: The adenosquamous carcinoma of the gallbladder is a rare variant accounting for only 1-4% of all primary gallbladder carcinoma. Regardless of the histological types, all gallbladder carcinomas have silent and rapid progression resulting in delayed diagnosis and poor prognosis. Even with medical and/or surgical interventions, the median survival of patients with adenosquamous carcinoma, one of the histological variants, is less than a year.
View Article and Find Full Text PDFSelection, a basic and crucial step of breeding, can be made efficient through the estimates of genetic parameters. Ten multi-company's maize hybrids and two Nepalese maize hybrids were used as standard checks and evaluated in a randomized complete block design with three replications. Analysis of variance for different characters revealed significant differences for most of the characters among the genotypes used.
View Article and Find Full Text PDFBackground: Pancreaticojejunostomy (PJ) is the ''Achilles heel" of pancreaticoduodenectomy (PD) which affects perioperative as well as oncological outcomes. However, there is a lack of information about the superiority of the type of anastomosis in terms of overall morbidity and postoperative pancreatic fistula (POPF) after PD. Here, we compare the outcomes of modified Blumgart PJ with the dunking technique of PJ.
View Article and Find Full Text PDFIntroduction And Importance: Primary sacral and presacral lesions are uncommon and pose a significant diagnostic dilemma. Retrorectal schwannoma is a benign primary presacral lesion that is extremely rare and presents with non-specific symptoms.
Case Presentation: A 42-years-old, female patient was admitted for lower-back pain for seven days.
Geographically, Jumla is a Himalayan mountainous region located in the Karnali Province of Nepal. It has a beautiful landscape with abundant plant and animal species and is rich in biodiversity. Jumli Marshi has been cultivated since prehistoric times.
View Article and Find Full Text PDFPresacral dermoid cysts are rare, benign tumors of developmental origin that primarily affect women. Surgical resection is the mainstay of treatment for these cysts, even if asymptomatic, with the laparoscopic approach being safer and more efficient.
View Article and Find Full Text PDFIntroduction And Importance: Jejunal diverticula are usually asymptomatic and are discovered incidentally. While rare, their complications may be life-threatening. They should be considered as differential diagnoses in undiagnosed complaints of chronic abdominal pain, malabsorption, anemia, gastrointestinal bleed and intestinal obstruction.
View Article and Find Full Text PDFIntroduction And Importance: Cecal gastrointestinal stromal tumors (GIST) constitute a rarer subtype of all GISTs. Rarely, it can present with ileocolic intussusception in adults making it a challenging diagnosis due to non-specific clinical features.
Case Presentation: A 30-year previously healthy woman presented with lower abdominal pain and a distended abdomen who was subsequently diagnosed with ileocolic intussusception on a CT scan.
Introduction And Importance: Common Hepatic Artery (CHA) Pseudoaneurysm is a rare entity, attributed to infections, trauma, and upper abdominal surgery. Most cases occur after biliary and pancreatic surgery. CHA pseudoaneurysm after total gastrectomy is uncommon and can be devastating.
View Article and Find Full Text PDFHybridization plays a vital role in increasing the production and productivity of maize. Evaluating maize hybrids in a specific environment is a key task for the hybrid maize program. The objective of this study was to identify a promising maize hybrid for winter planting in inner terai regions.
View Article and Find Full Text PDFCongenital intercostal liver herniation is a rare entity. The exact etiology of congenital intercostal liver herniation is unknown. Left sided intercostal herniation is even rarer.
View Article and Find Full Text PDFObjectives: A field experiment was conducted to evaluate Soil Plant Analysis Development (SPAD) value in different age and leaf of maize hybrid and correlating with grain yield. Ten maize hybrids were replicated thricely under Randomized Complete Block Design (RCBD) during winter of 2018. SPAD value was measured by SPAD 502 plus meter.
View Article and Find Full Text PDFWheat is the third most important cereal crop in Nepal after rice and maize both in area and production, but its productivity of 2.3 tonne ha is very less compared to other developed countries (6 tonne ha for Switzerland and China) in the world. The main cause of low wheat yield in Nepal is the improper and inadequate use of fertilizer devoid of site specific nutrient management practices.
View Article and Find Full Text PDFBackground: Chronic pancreatitis is a progressive and persistent inflammatory disease resulting in pancreatic insufficiency leading to diabetes and steatorrhea. Abdominal pain is the most debilitating feature and is often refractory to treatment. Medical management with adequate analgesia and replacement of pancreatic enzyme supplements is the first line in management of chronic pancreatitis.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
February 2017
Background: Improper dietary intake pattern in women of reproductive age in Nepal has resulted in the deficiency of essential nutrients. Adequate nutritional status and proper dietary intake pattern of women improves maternal and child health. The objective of this study was to assess the nutritional status and dietary intake pattern among the women and associated factors.
View Article and Find Full Text PDFJNMA J Nepal Med Assoc
May 2015
Introduction: Gastric cancer perforation can occurs in advanced stage of the disease and is often associated with a high morbidity and mortality. Peritonitis due to perforation needs emergency laparotomy and different surgical procedures can be performed for definitive treatment. Surgical procedures largely depend on the stage of the disease and general condition of the patient.
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