Circ_0069094 regulates malignant phenotype and paclitaxel resistance in breast cancer cells via targeting the miR-136-5p/YWHAZ axis.

Background: Breast cancer is one of the most malignant cancers. Increasing evidence suggests that circular RNAs (circRNAs) are involved in breast cancer progression through sponging microRNA (miRNA). However, the underlying molecular mechanisms of circ_0069094 in breast cancer are unclear.

[Progress on eco-technology classification in ecologically vulnerable regions of China].

Ecological technology is the core of ecological environment governance and restoration in ecologically vulnerable regions. A reasonable classification method is the basis for induction and summary of ecological techno-logy, which is of great significance to classify and solve ecological environmental problems and evaluate the effects of ecological technology implementation. However, there is still no standard method for the classification of ecological technology.

The ketogenic diet could improve the efficacy of curcumin and Oldenlandia diffusa extract in the treatment of gastric cancer by increasing miR340 expression and apoptosis mediated by autophagy, oxidative stress, and angiogenesis.

The pathogenesis of gastric cancer is a multistage process that involves glucose metabolism, inflammation, oxidative damage, angiogenesis, autophagy, and apoptosis. Moreover, microRNA-340 (miR340) also plays a vital role in tumorigenesis and the biology of gastric cancer as an epigenetic factor. It seems that the use of ketogenic diets (KDs) and plant extracts that have antitumor, anti-inflammatory, and antioxidant properties can be good treatment options to cure gastric cancer.

Circ-TFF1 Facilitates Breast Cancer Development via Regulation of miR-338-3p/FGFR1 Axis.

Some circular RNAs (circRNAs) have been verified to act as essential regulators in the progression of breast cancer (BC). We aimed to investigate the role of circRNA trefoil factor 1 (circ-TFF1) in BC progression. The expression of circ-TFF1, microRNA-338-3p (miR-338-3p) and fibroblast growth factor receptor 1 (FGFR1) mRNA was measured by quantitative real-time polymerase chain reaction (qRT-PCR).

Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways.

Colorectal cancer (CRC) is the third most common malignancy and one of the leading causes of cancer-related death among men worldwide. CRC is a multifactor digestive pathology, which is a huge problem faced not only by clinicians but also by researchers. Importantly, a unique feature of CRC is the dysregulation of molecular signaling pathways.

Downregulation of Krüppel‑like factor 1 inhibits the metastasis and invasion of cervical cancer cells.

Cervical cancer is one of the most common malignancies that seriously threatens women's health. Krüppel‑like factors (KLFs) have been reported to be associated with the progression of cervical cancer. The role of KLF1 in cervical cancer, which still remains unclear, was investigated in the present study.

DNA methylation biomarkers for the occurrence of lung adenocarcinoma from TCGA data mining.

The development of lung cancer is a combination of multifactor, multistage, and multiple genetic alterations processes. DNA methylation is an important factor. Currently, the study on the genome-scale epigenetic modification for studying the pathogenesis of lung cancer is still lacking.

[Effects of land use/cover change on runoff sediment discharge in typical watershed in Loess gullied-hilly region of China].

By using the measurement technique of dynamic hydrological process and the estimation method of landscape ecology, this paper studied the effects of 1986-2004 land use/cover change (LUCC) on the runoff sediment discharge in the Luoyugou watershed in Tianshui of Gansu Province in third sub-region of Loess Plateau. The results showed that the LUCC in Luoyugou watershed had significant effects on the annual sediment yield. In 1995-2004, the sediment discharge was reduced by approximately 63.