[Palliative resection in esophageal cancer].

A 20-year experience of treatment of 633 patients with cancer of the thoracic esophagus has been evaluated. Far advanced disease was diagnosed in 384 (60.7%).

[Single-stage operations for synchronous multiple primary and metastatic cancer of the lung and other organs].

The work presents an experience with the diagnosing of synchronous tumors of double localization in 256 patients. Operations were performed on 146 of them. Single-stage operations were made in 55 cases.

[Prophylaxis and treatment of primary insufficiency of bronchial stump after pneumonectomy].

Efficacy of gel DAM+ in bronchial surgery was evaluated in experimental and clinical studies. In clinical practice DAM+ was used for treatment of 22 patients with insufficiency of bronchial stump, and in 12 patients with high risk of stump insufficiency this gel was administered into submucosal layer before stump closure. It is demonstrated that administration of DAM+ gel into submucosal layer is simple and effective method of treatment and prophylaxis of bronchial stump insufficiency.

[Diagnosis and treatment of lung cancer associated with paracancerous changes in the thoracic cavity].

Incidence of lung cancer associated with secondary paracancerous changes is known to range 13.7-30%. Since they reveal such clinical symptoms as pneumonia or empyema, most out-patients with complicated cancers are referred to general wards.

[Surgical treatment of lung cancer complicated by intrathoracic inflammatory paracancrous alterations].

An experience with diagnostics and surgical treatment of 291 patients with complicated course of lung cancer is described with special reference to specificities of the clinical course, preoperative management and operation technique. It was shown that the purposeful preoperative management allowed the assessment of the patients, previously thought to be inoperable, to be revised in 25% of cases, and the frequency of postoperative complications and lethality to be reduced to 14 and 3.5% respectively.

[Surgical treatment of lung cancer patients with brain metastases].

The authors present an experience with diagnosing and treatment of 16 patients suffering from lung cancer with solitary metastasis into the brain. The examination performed has shown that in 7 out of 16 patients the surgical treatment was found to be not expedient. This solution was based on the detection of an extensive spread of lung cancer: multiple metastasis outside the thoracic cavity and the brain or inside the brain, and in one case--due to a considerable reduction of indices of the functional and reserve capacities of respiration and blood circulation.

[The endoscopic treatment of bronchial fistulas by submucosal injections].

A total of 21 patients (aged 30-72) with bronchial stump fistulas (307 mm) were treated by a newly developed method of treatment of purulent-destructive pulmonary diseases. This technique represents a gradual narrowing of the bronchial fistula lumen due to infiltrate formation in the submucosal bronchial layer. The volume formation substance biopolymer "DAM+", hydrogenous biopolymer with ions of silver "Argiform" for endoprosthesis of the soft tissues, is injected into the submucosal bronchial layer.

[One-stage operations on the lungs and other organs in multifocal and metastatic cancer].

Surgical treatment of 135 patients with multifocal and metastatic cancer of the lungs and other organs is analyzed. The absence of absolute differential diagnostic differences between true poly-neoplasia and synchronous or metachronous solitary metastases leads to extension of indications to surgical treatment of these patients. Surgical procedures were performed in 109 patients, 37 (33.

[The diagnostic and curative strategy for spontaneous pneumothorax].

The article presents the authors' experiences with treatment of 292 patients with spontaneous pneumothorax. Results of the suction drainage (188 patients), thoracoscopy and talc pleurodesis (43 patients), videothoracoscopic surgical treatment and pleurodesis (61 patients) are compared. The proposed algorithm allowed to make recurrences 2.

[Surgical treatment of patients with primary-multiple cancer and involvement of the lungs and other organs].

The article presents experiences with diagnosis and treatment of 43 patients with synchronous primary-multiple cancer of the lung with localization of one and more tumors in the lung which makes 4.8% of the number of the examined and treated patients with lung cancer in the clinic of thoracic surgery of the Military Medical Academy during 1995-2003. In 10 patients with primary-multiple cancer the injury of the lungs was combined with a tumor of the gastro-intestinal tract, in 13 with cancer of the urinary system, in 19 patients the synchronously developing tumor was localized in the lungs with a bilateral affection and in 1 case in different lobes of one lung.

[Surgery in the treatment of metastatic lesions of the lung and pleura].

An experience with treatment of 53 patients with intrapulmonary metastases of malignant tumors of different nature included 65 surgical interventions, among them there were bilateral operations and reoperations. During the postoperative period complications took place in 5 cases (9.1%).

[Lung cancer complicated by paraneoplastic state].

A 10 year experience with dealing with the problem of surgical treatment of patients with lung cancer complicated by paracancrosis is described. Paracancrosis is characterized by the appearance and manifestation of different inflammatory and pyodestructive alterations in the thoracic cavity resulting from the tumor. The paracancrosis pathogenesis, its clinical symptoms, methods of diagnosis are described.

[Extended and combined operations for lung cancer].

On the basis of classificating components of the TNM system 1720 patients with "later" stages of the development of lung cancer were selected from 3000 patients with this disease operated upon in the clinic for many years. Specific features of performing extended and extended combined operative interventions, treatment at the postoperative period are described and substantiated. After their discharge from the hospital correspondingly 26% and 21.

Local administration of interleukin-1beta for the treatment of lung abscesses induces neutrophil activation and changes in proinflammation cytokine production.

Interleukin-1 (IL-1) is a potent immunostimulatory molecule with broad range biological activity that limits its systemic application in humans. Alternatively, IL-1 can be applied locally, directly to the inflammatory site for stimulation of local defense mechanisms, without activating an acute phase response. IL-1beta preparations have been successfully used for local therapy of patients with purulent bacterial lung abscesses who were resistant to usual antibiotic treatment.

[Local use of recombinant interleukin-1 beta in the complex treatment of patients with acute lung abscess].

An analysis of results of examination and treatment of 59 patients with a prolonged duration of acute abscesses of the lungs has shown the influence of immune disorders on the dynamics of the development and outcome of pyo-destructive disease in the lung. The indications to local immunosubstituting therapy were determined. A new original method of administration and a scheme of prescription of the medicine Betaleukin are proposed.

[Diagnostic and surgical approach in the combined thoracic trauma complicated by pulmonary and heart contusion].

Experience of treatment of 782 injured persons with combined thoracic trauma was summarized. Of the total number of injured persons with pulmonary contusion 177 (control group) were treated using conventional methods and 165 (basic group)--an early active operative tactics. Of the total number of injured persons in 150 with heart contusion (basic group) the cardiotropic therapy conduction was started from the hospitalization moment and in 134 (control group)--from the second day and later.

[Diagnosis and correction of pathological changes of the tracheobronchial tree during lung surgery].

In 32% of patients operated on the lungs various changes in the tracheobronchial tree develop as early as during the surgical intervention. They are of determining significance in pathogenesis of postoperative disorders in the external breathing function. Bronchoscopy is the most effective method of diagnosis and of timely correction of these disorders during operation on the lungs.

[Classification of surgical procedures in lung cancer].

Various aspects of classification of surgical operations in cancer of the lung are presented. The authors suggest their supplement and changes in systematization of surgical interventions in malignant tumors of the lungs published by V.I.

[Long-term transbronchial catheterization of the destructive cavities in the treatment of acute lung abscesses with disordered bronchial patency].

High curative efficiency of prolonged transbronchial catheterization of destruction cavities of the lung is shown on the basis of results of treatment of 80 patients. Possible risk factors and preventive measures in using this method are described.

[Endolymphatic antibiotic therapy in the combined treatment of acute lung abscesses].

The concentration of antibiotics in the pulmonary tissue, regional lymph collectors was studied after direct and indirect endolymphatic infusions. The effectiveness of indirect endolymphatic antibiotic therapy is shown for treatment of purulent diseases of the lungs.

[General biological characteristics of the etiology of postoperative complications in patients with surgical diseases of the lungs].

The causes of lethal outcomes (n = 60) and postoperative complications which occurred in 26.1% of 610 patients operated on for lung cancer were investigated with due consideration for the regularities of thermodynamics of nonequilibrium processes and theory of disasters. A total systems pathological inflammatory reaction, which augments the injury by many times and develops as a result of inadequate anesthesiological protection, underlies the development of the most unfavorable variant of response to surgery leading to life-threatening complications, such as pneumonia, thromboembolism, or ulcerative hemorrhages.