Publications by authors named "Birute Varanaviciene"
Low-molecular-weight heparins: pharmacoeconomic decision modeling based on meta-analysis data.
Int J Technol Assess Health Care
July 2010
Objectives: The aim of this study was to compare efficacy, safety, and consumption of low-molecular-weight heparins with unfractionated heparin, and to develop a pharmacoeconomic decision model based on meta-analysis data.
Methods: Review and meta-analysis were performed of published randomized control trials directly comparing the safety and efficacy of low-molecular-weight heparins (LMWHs)-that is, nadroparin, enoxaparin, and dalteparin-and unfractionated heparin (UFH) was performed by two reviewers using inclusion/exclusion criteria based on the research objectives. The value of fixed effects and random effects odds ratio (95 percent confidence interval) was calculated for each trial for the composite end point.
Objectives: To collect the data about the consumption of digoxin, evaluate the tendencies towards usage of this drug during 2004-2007, and to find departments, which cover the main part of digoxin consumption in a tertiary hospital. To evaluate the intensity of serum digoxin concentration measurements during 2005-2007.
Material And Methods: Our study was carried out in a tertiary hospital with 2600 beds and 63 departments.
Summary Objective: The main goal of this study was to evaluate the variation of antibiotic consumption and relation between antibiotic consumption and microorganism resistance.
Material And Methods: This analysis was performed in one of Lithuanian tertiary hospitals. The defined daily dose (DDD) analysis was performed to express drug consumption per every 100 occupied bed days (OBDs) for single units in clinical departments.