Publications by authors named "Biruk Legese"
Article Synopsis
- Malaria significantly impacts blood coagulation parameters and platelet counts, indicating a relationship between disease severity and these measurements.
- A study involving 240 participants found that a high percentage of malaria patients experienced prolonged prothrombin time (PT), international normalization ratio (INR), and activated partial thromboplastin time (APTT), compared to healthy controls.
- The findings showed that as malaria parasitemia increased, PT, APTT, and INR values elevated, while platelet counts decreased, highlighting the importance of monitoring coagulation in malaria patients.
Article Synopsis
- A study conducted in Northwest Ethiopia found a 16.4% prevalence of opportunistic intestinal coccidian parasites (OICPs) among HIV/AIDS patients attending an ART clinic.
- Factors such as drinking surface water, alcohol consumption, diarrhea, medication dropout, and low CD4 counts were significantly associated with higher rates of these infections.
- The findings highlight that OICPs continue to be a major health concern for people living with HIV/AIDS, contributing to increased morbidity and mortality.
Background: The preanalytical phase encompasses the time between the clinician's test order to the sample being ready for analysis. Of all errors during the laboratory diagnostic process,70 % appeared in the pre-analytical phase. In clinical laboratories, it is crucial to ensure proper specimen collection and handling, which is essential to guarantee quality assessment, monitoring process standardization, improving performance, and ensuring patient safety.
View Article and Find Full Text PDFBackground: Data about the distribution of ABO and RhD blood groups is important for effective blood utilization, which is maintained by identifying the most clinically required blood type. However, there is a scarcity of data in Ethiopia about the distribution of ABO and RhD blood groups among blood-transfused patients, particularly in the study area.
Objective: To determine the frequency of ABO and RhD blood groups among blood transfused patients at Dessie Comprehensive Specialized Hospital, Northern Ethiopia, 2023.
Background: The fourth most common cancer in women worldwide is cervical cancer. Over 87% of deaths from cervical cancer occur in developing nations. One of the risks of developing cervical cancer is the use of oral contraceptives.
View Article and Find Full Text PDFBackground: Diabetes mellitus (DM) is a worldwide public health problem. The burden of diabetes has been continuously increasing from day to day, especially in developing countries like Ethiopia. Globally, half of all cases of diabetes mellitus are undiagnosed.
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- Tuberculosis (TB) remains a significant global health issue, especially in developing countries, and this study assessed treatment outcomes in South Gondar, Ethiopia, during 2023.
- A retrospective analysis of 400 TB patients revealed a treatment success rate of 89.0%, which is below the global target of over 90% for 2025, with HIV-positive patients facing higher risks for unsuccessful treatment.
- Key findings indicated that TB patients who are HIV-positive are nearly three times more likely to have poor treatment outcomes, while patients with sputum-positive TB showed better treatment success rates.
Background: Asthma is a diverse disease with various etiologic bases. Severe asthma can be associated with increased mortality, hospitalization, and decreased quality of life for asthma patients. High blood eosinophil counts were associated with severe asthma, but recent studies have failed to confirm this as a marker of severe asthma among adult asthma patients.
View Article and Find Full Text PDFBackground: Besides their clinical significance in blood transfusion medicine, ABO and Rh blood group antigens were found to be associated with many non-infectious and infectious diseases. This investigation aimed to assess the association of ABO and Rh blood group antigens with transfusion transmissible infections (TTIs).
Methods And Materials: A cross-sectional retrospective investigation was conducted on 27,027 blood donors at Bahir Dar blood bank, from March 24/2019 to October 21/2021.
Article Synopsis
- Soil-transmitted helminths (STH) are prevalent infections among school children in low- and middle-income countries, particularly impacting those with poor hygiene and sanitation practices, with a focus on Tachgayint woreda, Ethiopia.
- A study conducted on 325 children found a 36.0% prevalence of STH infections, with Ascaris lumbricoides being the most common type, and all infections were light intensity.
- Risk factors identified included not wearing shoes and having untrimmed fingernails, highlighting the need for improved hygiene and preventive measures to address these infections among children.
Background: Among the blood group antigens identified, ABO and Rhesus are the most important in transfusion medicine. ABO blood group antigens are the most immunogenic followed by Rhesus (D antigen). These blood groups' frequency distribution varies among different regions and races of the world.
View Article and Find Full Text PDFBackground: ABO and Rh blood group antigens are thought to be among genetic determinants of type 2 diabetes mellitus. Identification of blood group phenotypes are more associated with type 2 diabetes mellitus. It will be helpful for individuals who are susceptible blood groups to take care of themselves by avoiding other predisposing factors and taking preventive measures.
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