Publications by authors named "Birol S"

Article Synopsis
  • Platelets are tiny cells in our blood that help stop bleeding, and they come from larger cells called megakaryocytes.
  • Researchers found that when they send megakaryocytes through mouse lungs, they can produce a huge number of platelets, sometimes up to 3000 from one cell!
  • The study also looked at how things like oxygen and the lungs' structure help in making platelets, and they discovered that a special protein, Tropomyosin 4, is important for the final stage of making platelets.
View Article and Find Full Text PDF

Atherosclerosis is a long-term disease process of the vascular system that is characterized by the formation of atherosclerotic plaques, which are inflammatory regions on medium and large-sized arteries. There are many factors contributing to plaque formation, such as changes in shear stress levels, rupture of endothelial cells, accumulation of lipids, and recruitment of leukocytes. Shear stress is one of the main factors that regulates the homeostasis of the circulatory system; therefore, sudden and chronic changes in shear stress may cause severe pathological conditions.

View Article and Find Full Text PDF

. To perform totally extraperitoneal repair of a hernia, it is essential to create a working space for the placement of instruments. In this study, we aimed to compare balloon dissection (BD) and camera or telescopic dissection (CD) with respect to the surgical outcomes, without considering the cost-effectiveness.

View Article and Find Full Text PDF

Many diseases have their treatment options narrowed and end up being fatal if detected during later stages. As a consequence, point-of-care devices have an increasing importance for routine screening applications in the health sector due to their portability, fast analyses and decreased cost. For that purpose, a multifunctional chip was developed and tested using gold nanoprobes to perform RNA optical detection inside a microfluidic chip without the need of molecular amplification steps.

View Article and Find Full Text PDF

A 22 year-old male patient was admitted to our clinic with complaints of swelling and pain at the left groin area as well as inability to palpate his right testicle. The patient was diagnosed as right undescended testicle accompanied by left indirect inguinal hernia. According to the scrotal Doppler ultrasonography the right undescended testicle was localized in the inguinal canal very close to the inner ring.

View Article and Find Full Text PDF

Background: Liver hydatidosis may lead to serious morbidity due to biliary complications, the management for which endoscopic sphincterotomy (ES) and biliary drainage are very efficient. We evaluated the effectiveness of endoscopic treatment for complications of hepatic hydatid disease.

Methods: We retrospectively reviewed endoscopic retrograde cholangiopancreatography (ERCP) procedures performed between January 2000 and December 2009 and compared laboratory findings, localization of the lesions and ERCP procedures applied between patients with and without jaundice.

View Article and Find Full Text PDF

Thyroid gland is an important endocrine organ because of its functions. Although the morbidity and mortality of thyroid surgery have decreased markedly, serious complications may still occur. The aim of this retrospective study was to identify the factors influencing the complications in benign nodular thyroid surgery.

View Article and Find Full Text PDF

Background And Purpose: Fournier's gangrene (FG) is a rare, rapidly progressive, fulminant form of necrotizing fasciitis of the genital, perianal and perineal regions. Our aim is to investigate the clinical signs, symptoms and factors which affect the clinical results of patients with FG in our clinic.

Patients And Methods: 20 patients having FG were admitted to our department during the past 6-year period.

View Article and Find Full Text PDF

Background And Purpose: Intra-abdominal pressure created during laparoscopic cholecystectomy is accepted as a factor for postoperative pain. In this prospective, randomized, clinical study, the goal is to determine the effects of different intra-abdominal pressure values on visceral type pain.

Materials And Methods: Sixty women who underwent laparoscopic cholecystectomy were included in this study.

View Article and Find Full Text PDF