Healthcare users' evaluation of general practice - a survey among Danish men aged 45 to 70 years.

Background: Knowledge about healthcare users' evaluation of general practice is relatively limited.

Aim: We aimed to investigate evaluations in Danish men of general practice healthcare and of different aspects of general practitioners' (GPs) communication with patients.

Design & Setting: Secondary analyses of data from a web-based survey in 6756 Danish men aged 45-70 years (30% response rate) using municipality-level information from registries, self-reported sociodemographic data, personality characteristics, and five-point Likert scale evaluations of healthcare and communication in general practice.

Perceptions Among Mental Health Professionals Regarding the Intrusiveness of Coercive Measures: A Danish Regional Survey.

Background: Although hotly disputed, coercive measures are widely used in mental health services globally. In Denmark, to ensure the rights of patients, special psychiatric legislation that emphasizes the imperative to always use the least intrusive intervention has been implemented. This raises the question of which coercive measures are perceived as being less intrusive than others.

Methodological Approaches for Analyzing Medication Error Reports in Patient Safety Reporting Systems: A Scoping Review.

Background: Medication errors (MEs) pose risks to patient safety, resulting in substantial economic costs. To enhance patient safety and learning from incidents, health care and pharmacovigilance organizations systematically collect ME data through reporting systems. Despite the growing literature on MEs in reporting systems, an overview of methods used to analyze them is lacking.

Cardiac anatomic digital twins: findings from a single national centre.

Aims: New three-dimensional cardiac visualization technologies are increasingly employed for anatomic digital twins in pre-operative planning. However, the role and influence of extended reality (virtual, augmented, or mixed) within heart team settings remain unclear. We aimed to assess the impact of mixed reality visualization of the intracardiac anatomy on surgical decision-making in patients with complex heart defects.

Right ventricular remodelling and long-term survival after pulmonary endarterectomy versus balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension.

Background: Pulmonary endarterectomy (PEA) is the treatment of choice for chronic thromboembolic pulmonary hypertension (CTEPH), while balloon pulmonary angioplasty (BPA) is an alternative for inoperable patients. We aimed to compare right ventricular (RV) remodelling and late survival after PEA and BPA.

Methods: In this prospective observational cohort study, we performed echocardiography at baseline and follow-up in patients with CTEPH treated with PEA (n=54) or BPA (n=44) between 2011 and 2022.

Legislation and policy for involuntary mental healthcare across countries in the FOSTREN network: rationale, development of mapping survey and protocol.

Background: Several countries are currently revising or have already revised their mental health laws to align with the global movement to reduce the use of coercive care. No government has yet fully implemented the recommendation of the United Nations Convention on the Rights of Persons with Disabilities (UNCRPD) to eliminate the use of coercion in mental healthcare. Consequently, the international field of mental health law and policy is in a degree of flux.

Chronic oral LPS administration does not increase inflammation or induce metabolic dysregulation in mice fed a western-style diet.

Introduction: Lipopolysaccharides (LPS) present in the intestine are suggested to enter the bloodstream after consumption of high-fat diets and cause systemic inflammation and metabolic dysregulation through a process named "metabolic endotoxemia." This study aimed to determine the role of orally administered LPS to mice in the early stage of chronic low-grade inflammation induced by diet.

Methods: We supplemented the drinking water with derived LPS to mice fed either high-fat Western-style diet (WSD) or standard chow (SC) for 7 weeks ( = 16-17).

Importance of GP contact on readmission rate following psychiatric acute care: A Danish Nationwide study.

Unlabelled: Insufficient acute psychiatric care substantially impacts patient well-being and healthcare quality. Early readmissions after discharge from psychiatric care are common, and preventing these is important for the patients as well as appropriate resource allocation. The relationship between post-discharge general practitioner (GP) contact and readmission rates remains to be explored, as does the association between pre-hospital GP contact and post-discharge engagement.

Impact of whole-genome duplications on structural variant evolution in Cochlearia.

Polyploidy, the result of whole-genome duplication (WGD), is a major driver of eukaryote evolution. Yet WGDs are hugely disruptive mutations, and we still lack a clear understanding of their fitness consequences. Here, we study whether WGDs result in greater diversity of genomic structural variants (SVs) and how they influence evolutionary dynamics in a plant genus, Cochlearia (Brassicaceae).

Abolition of coercion in mental health services - A European survey of feasibility.

Background: In 2019, the Council of Europe agreed to urge member states to take steps toward total abolition of psychiatric coercive measures.

Aims: To test if this aspiration is perceived as realistic and what the alternative would be in the event of a total abolition, we surveyed members of the European FOSTREN network of mental health practitioners and researchers, which is specifically dedicated to exchanging knowledge on reducing psychiatric coercion to its minimum.

Methods: Web-based survey.

Associations between knowledge of health issues and health care satisfaction and propensity to complain: a cross-sectional survey of adult men in Denmark.

Objectives: The objective of this study was to investigate associations between knowledge of health issues and healthcare satisfaction and propensity to complain including the association between knowledge and greater patient involvement.

Design: The present study is a secondary analysis of a larger cross-sectional case vignette survey.

Setting: Survey conducted in adult Danish men.

Mental health patients' preferences regarding restrictive interventions: An integrative review.

Unlabelled: WHAT IS KNOWN ON THE SUBJECT?: The use of restrictive interventions is described as a violation of patients' rights and autonomy. It must only be used as a last resort to manage dangerous behaviour, to prevent or reduce the risk of mental health patients harming themselves or others. International mental health policy and legislation agree that when restrictive interventions are applied, the least restrictive alternative should be chosen.

An evolutionary timeline of the oxytocin signaling pathway.

Oxytocin is a neuropeptide associated with both psychological and somatic processes like parturition and social bonding. Although oxytocin homologs have been identified in many species, the evolutionary timeline of the entire oxytocin signaling gene pathway has yet to be described. Using protein sequence similarity searches, microsynteny, and phylostratigraphy, we assigned the genes supporting the oxytocin pathway to different phylostrata based on when we found they likely arose in evolution.

Variation in opinions on coercion use among mental healthcare professionals: a questionnaire study.

Introduction: Even if coercive measures are widely applied in psychiatry and have numerous well-known drawbacks, there is limited known on the agreement among mental healthcare professionals' opinions on their use. In a questionnaire study using standardized scenarios, we investigated variation in staff opinions on coercion.

Methods: In a web-based survey distributed to staff at three psychiatry hospitals, respondents were asked to consider if and what coercion to use by introducing two hypothetical scenarios involving involuntary psychiatric admission and in-hospital coercion.

Video based hand gesture recognition dataset using thermal camera.

The dataset includes thermal videos of various hand gestures captured by the FLIR Lepton Thermal Camera. A large dataset is created to accurately classify hand gestures captured from eleven different individuals. The dataset consists of 9 classes corresponding to various hand gestures from different people collected at different time instances with complex backgrounds.

How Does Selfing Affect the Pace and Process of Speciation?

Surprisingly little attention has been given to the impact of selfing on speciation, even though selfing reduces gene flow between populations and affects other key population genetics parameters. Here we review recent theoretical work and compile empirical data from crossing experiments and genomic and phylogenetic studies to assess the effect of mating systems on the speciation process. In accordance with theoretical predictions, we find that accumulation of hybrid incompatibilities seems to be accelerated in selfers, but there is so far limited empirical support for a predicted bias toward underdominant loci.

Staff responses to interventions aiming to reduce mechanical restraint in adult mental health inpatient settings: a questionnaire-based survey.

Purpose: To explore mental health staff's responses towards interventions designed to reduce the use of mechanical restraint (MR) in adult mental health inpatient settings.

Methods: We conducted a cross-sectional, questionnaire-based survey. The questionnaire, made available online REDCap, presented 20 interventions designed to reduce MR use.

Complaint behaviour among healthcare users: self-reported complaint experience and complaint proneness in adult men.

Aims: When patients are harmed by, or dissatisfied with, healthcare, only a minority will lodge a complaint or file a claim for compensation. This survey aimed to investigate complaint behaviour and inequalities in complaints using self-reports and hypothetical case vignettes.

Methods: Cross-sectional, web-based survey among 6755 Danish men aged 45-70 years (response rate=30%).

Identifying high-risk medications and error types in Danish patient safety database using disproportionality analysis.

Background: Medication error (ME) surveillance in Danish healthcare relies on the mandatory national incident reporting system, the Danish Patient Safety Database (DPSD). Individual case reviews and descriptive statistics with frequency counts are the most often used approaches when analyzing MEs in incident reporting systems, including the DPSD. However, incident reporting systems often generate a large number of reports and may suffer from underreporting; consequently, additional approaches are needed to overcome these challenges.

Using complaints from obstetric care for improving women's birth experiences - a cross sectional study.

Introduction: Staff shortages and quality in obstetric care is a concern in most healthcare systems and a hot topic in the public debate that has centred on complaints about deficient care. However there has been a lack of empirical data to back the debate. The aim of this study was to analyse and describe complaints in obstetric care.

Microbial experience through housing in a farmyard-type environment alters intestinal barrier properties in mouse colons.

To close the gap between ultra-hygienic research mouse models and the much more environmentally exposed conditions of humans, we have established a system where laboratory mice are raised under a full set of environmental factors present in a naturalistic, farmyard-type habitat-a process we have called feralization. In previous studies we have shown that feralized (Fer) mice were protected against colorectal cancer when compared to conventionally reared laboratory mice (Lab). However, the protective mechanisms remain to be elucidated.

Health Care Complaints and Professional Legal Responsibility - A Cross-Country Comparative Review.

One approach to stimulating patient safety and health care quality is through holding health care professionals legally responsible for their performance. Law and health care variation across countries, however, makes it difficult to get an overview and make comparisons of the personal legal responsibility of health care providers. This article describes health care professional liability and complaint measures in some European countries (UK, The Netherlands, Sweden and Denmark) and US.