Remodeling of strain energy function of common bile duct post obstruction.

Biliary duct obstruction is an important clinical condition that affects millions of people worldwide. We have previously shown that the common bile duct (CBD) undergoes significant growth and remodelling post obstruction. The mechanical stress-strain relation is expected to change due to growth and remodeling in response to obstruction and hence pressure-overload.

Mechanical properties of the porcine bile duct wall.

Background And Aim: The function of the common bile duct is to transport bile from the liver and the gall bladder to the duodenum. Since the bile duct is a distensible tube consisting mainly of connective tissue, it is important to obtain data on the passive mechanical wall properties. The aims of this study were to study morphometric and biomechanical wall properties during distension of the bile duct.

Indicial response functions of growth and remodeling of common bile duct postobstruction.

Biliary duct obstruction is an important clinical condition that stems from cholelithiasis, the neoplasm in the wall or, most commonly, gallbladder stones. The objective of this study is to understand the structural and mechanical remodeling of the common bile duct (CBD) postobstruction. Porcine CBD was ligated near the duodenum that increased the duct's pressure from 6.

Morphometric and biomechanical remodelling following reopening of the obstructed bile duct.

Obstruction in the common bile duct results in duct dilatation, increased wall thickness and stiffening of the wall. Whether these changes are reversible after release of the obstruction has not yet been studied in detail. The aim of this study was to create a porcine model for release of bile duct obstruction and to describe biomechanical and morphometric parameters in a time-dependent design after the reopening.