Synopsis of recent research by authors named "Birgit Roloff"
- Birgit Roloff's research focuses on the intracellular calcium dynamics in human skin cells, specifically investigating the impact of corticotropin-releasing factor and urocortin on Ca(2+) signaling.
- In her 2003 study, she utilized confocal laser scanning microscopy to analyze various human skin cell types, including melanoma cells, neonatal melanocytes, and keratinocytes, to discern their responses to hormonal stimulation.
- Key findings revealed that the increase in intracellular calcium concentration was primarily due to calcium influx through voltage-activated calcium channels, dismissing the involvement of cyclic nucleotide-gated ion channels.