Publications by authors named "Birgit Nierula"

Article Synopsis
  • The spinal cord plays a crucial role in brain-body communication, but traditional noninvasive recording methods in humans face significant challenges.
  • Researchers developed a new electrophysiological approach that uses high-density multichannel spinal recordings and advanced spatial-filtering analyses, allowing for detailed timing and sensitivity in spinal cord response assessments.
  • This method was further expanded to include simultaneous recordings from peripheral, spinal, and cortical areas, providing evidence that integrative processing starts in the spinal cord, and was applied to study nociceptive responses during pain stimulation, paving the way for better understanding of brain-body interactions in health and disease.
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Changes in body representation may affect pain perception. The effect of a distorted body image, such as the telescoping effect in amputee patients, on pain perception, is unclear. This study aimed to investigate whether distorting an embodied virtual arm in virtual reality (simulating the telescoping effect in amputees) modulated pain perception and anticipatory responses to pain in healthy participants.

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Key Points: Embodiment of a virtual body was induced and its movements were controlled by two different brain-computer interface (BCI) paradigms - one based on signals from sensorimotor versus one from visual cortical areas. BCI-control of movements engenders agency, but not equally for all paradigms. Cortical sensorimotor activation correlates with agency and responsibility.

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The most robust and clear biological index differentiating persons with schizophrenia from healthy controls is the drastic reduction of the amplitude of their P300b event-related brain potential (ERP). However, the cause of that reduction remains obscure. Nevertheless, the P300b belongs to the family of the late posterior positivities (LPPs) which are closely related to the consciousness of the meaning of the stimulus in the task e.

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Unlabelled: Seeing one's own body has been reported to have analgesic properties. Analgesia has also been described when seeing an embodied virtual body colocated with the real one. However, there is controversy regarding whether this effect holds true when seeing an illusory-owned body part, such as during the rubber-hand illusion.

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The somatotopic layout of the primary somatosensory cortex is known for its fine spatial structure as delineated in single cell recordings and macroscopic EEG evoked responses. While a gross somatotopic layout has been revealed also for neuronal oscillations responding to sensorimotor stimulation of distant body parts (e.g.

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