The association between bacteria and outcome and the influence of sampling method, in people with a diabetic foot infection.

Purpose: Different bacteria lead to divers diabetic foot infections (DFIs), and some bacteria probably lead to higher amputation and mortality risks. We assessed mortality and amputation risk in relation to bacterial profiles in people DFI and investigated the role of sampling method.

Methods: We included people (> 18 years) with DFI in this retrospective study (2011-2020) at a Dutch tertiary care hospital.

Association of tumour and stroma PD-1, PD-L1, CD3, CD4 and CD8 expression with DCB and OS to nivolumab treatment in NSCLC patients pre-treated with chemotherapy.

Background: Immune checkpoint inhibitors are most beneficial in patients with high tumour PD-L1 expression. However, the use of PD-L1 expression is not straightforward. We investigated PD-L1 expression and immune cell (IC) infiltrates in non-small-cell lung cancer (NSCLC) patients treated with nivolumab.

Unmet supportive care needs in patients treated with total laryngectomy and its associated factors.

Background: The purpose of this study was to investigate unmet supportive care needs in patients treated with total laryngectomy and its associated factors.

Methods: In this cross-sectional study, 283 patients who underwent total laryngectomy completed questions on supportive care needs (Supportive Care Needs Survey [SCNS]). Median time since total laryngectomy surgery was 7 years (range 0-37 years).