Histopathology-derived modeling of prostate cancer tumor control probability: Implications for the dose to the tumor and the gland.

Purpose: To evaluate the impact of GTV-CTV dose differentiation by simulating response of prostate patients to radiotherapy, considering histopathology of prostatectomy specimens.

Material And Methods: Tumors' cell numbers (N0) and Gleason Scores (GS) were derived from histopathology of 25 specimens. Index lesions and tumors ⩾0.

Gross tumor volume and clinical target volume in prostate cancer: How do satellites relate to the index lesion.

Purpose: There is an increasing interest for dose differentiation in prostate radiotherapy. The purpose of our study was to analyze the spatial distribution of tumor satellites inside the prostate.

Methods And Materials: 61 prostatectomy specimens were stained with H&E.