Publications by authors named "Biquan Deng"
Article Synopsis
- The study investigates the effects of octanol on neuropathic pain induced by chronic constriction injury (CCI) in mice, focusing on its mechanism of action involving gap junctions and connexin 43 proteins.
- Male mice were grouped and subjected to CCI, with some receiving varying doses of octanol to assess pain responses and changes in nerve function, along with histopathological evaluations and protein analysis.
- Results showed that octanol significantly reduced pain sensitivity and functional loss while also altering histopathological changes, mainly through the inactivation of the Akt/mTOR signaling pathway, suggesting its potential as a treatment for neuropathic pain.
Background: Early and accurate detection of periprosthetic joint infection (PJI) after hip and/or knee arthroplasty remains challenging. This systematic review and meta-analysis of diagnostic test accuracy studies aimed to evaluate the diagnostic accuracy of serum and synovial fluid interleukin (IL)-6 in detecting PJI.
Methods: We searched 3 databases for studies through December 31, 2021, using medical sub-headings terms and keywords.