Publications by authors named "Bipindra Pandey"
In 2019, diabetes mellitus affected 9.3% of the global population and accounted for one in nine adult deaths. Plant-based antioxidants neutralize harmful free radicals, mitigate oxidative stress, and significantly prevent diabetes and its complications.
View Article and Find Full Text PDFLiver cancer is one of the most prevalent malignant diseases in humans and the second leading cause of cancer-related mortality globally. Angiopteris helferiana was mentioned as a possible anticancer herb according to ethnomedicinal applications. However, the molecular docking and chemical profiling of the bioactive phytoconstituents accountable for the reported anticancer action still require research.
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- The study evaluates the liver-protective effects of a traditional therapeutic plant (L.) in Nepal using a rat model to simulate liver damage through carbon tetrachloride (CCl) exposure.
- Male rats were divided into groups for treatment with different doses of the plant extract, and results showed significant improvement in liver enzyme levels and reduced liver injury after treatment.
- Molecular docking studies identified specific compounds in the extract (Beta-sitosterol and Betulinic acid) that demonstrated strong binding affinity to the CYP450 2E1 enzyme, supporting the extract's potential as a hepatoprotective agent.
To evaluate the extent to which pharmacies in Hetauda Sub-metropolitan City, Nepal adhere to the recommended practices outlined in the good pharmacy practice guidelines formulated by International Pharmaceutical Federation and draft developed by Nepal Pharmacy Council. Good Pharmacy Practice evaluates the safety, effectiveness, availability, and accessibility of medicines, ensuring their correct usage which is essential component of community pharmacies. Data was collected by visiting community pharmacies throughout Hetauda sub-metropolitan city.
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