Maintenance Impact of Large Dose of Vitamin C on Proinflammatory Cytokines, Insulin, and Electrocardiographic Parameters of Wistar Rats Following Partial Pancreatectomy.

We investigated serum tumor necrosis factor alpha (TNF-α) and interleukins (IL-6 and IL-8) in rats undergoing pancreatic wound healing after partial pancreatectomy. In addition, we studied the effects of partial pancreatectomy on the insulin and the electrocardiography (ECG). We proposed that vitamin C (VitC) could have maintenance impact on TNF-α, IL-6, IL-8, insulin, and ECG parameters of pancreatic wound healing of Wistar rats that had partial pancreatectomy surgery, if administered in large dose.

Thirty days oral Aframomum melegueta extract elicited analgesic effect but influenced cytochrome p4501BI, cardiac troponin T, testicular alfa-fetoprotein and other biomarkers in rats.

Ethnopharmacological Relevance: Pain is the commonest symptom of a disease and the percentage of persons manifesting one form of pain is growing globally. Aframomum melegueta (AM) is commonly used by traditional doctors as medication for many ailments such as body pains and rheumatism because it possesses anti-inflammatory, anti-allergenic, antiviral, anti-ageing and anti-tumour phytochemical agents.

Aim Of The Study: Traditionally a botanical remedy in the management of pain was assessed.

Serospatial epidemiology of zoonotic Coxiella burnetii in a cross section of cattle and small ruminants in northern Nigeria.

The persistent and highly transmissible Coxiella burnetii is a neglected infection that negatively affects reproductive parameters of livestock. It is also of zoonotic importance and has been reported to cause devastating human infections globally. Domestic ruminants represent the most frequent source of human infection.

Anti-anaemic effect of ethanol leaf extract of on cyclophosphomide-induced anaemia in rats.

Background: The folkloric claim that (Chaya) could ameliorate anaemia requires scientific revalidation in anaemic models.

Objective: The aim of this study is to investigate the anti-anaemic effect of on cyclophosphamide-induced anaemia in rats.

Methods: The leaves of were collected, dried and extracted with ethanol.

Methanolic leaf extract of improves the survivability rate, weight gain and histopathological changes of Wister rats infected with .

Trypanosomosis is a major disease of Man and animals. This study investigated the effect of leaf extract on the survivability rate, weight gain and histopathological changes of Wister rats experimentally infected with . A total of thirty (30) rats randomly divided into six groups (A-F).

Toxicological evaluation of the aqueous extract of Acalypha wilkesiana in Wistar albino rats.

Background: Acalypha wilkesiana (Euphorbiaceae) is highly accepted for traditional treatment of human plasmodiasis in Africa.

Methods: The toxicological effects of the aqueous leaf extract of A. wilkesiana were studied in 45 male and female Wistar albino rats.