Precise photothermal treatment of bacterial infection mediated by charge-switchable nanoplatform with acylsulfonamide betaine surface.

Photothermal therapy (PTT) offers a promising approach for the treatment of drug-resistant bacterial-infected wounds, yet it requires precise targeting of thermal damage to bacteria rather than healthy tissues. Herein, ultrasmall CuS NPs modified with polyzwitterion containing acylsulfonamide betaine (PCBSA@CuS), which provides a sensitive and reversible charge conversion around pH 6.8, are used to enhance the healing of bacteria-infected wounds.

Fabrication of antimicrobial cationic hydrogels driven by physically and chemically crosslinking for wound healing.

The wound therapy based on antibiotic delivery inevitably leads to the emergence of drug resistance. Hydrogel biomaterials with inherent antibacterial activities have emerged as promising candidates for addressing this issue. However, developing an inherently antibacterial hydrogel through simple and facile strategies to promote localized wound infection healing remains a challenge.

Hectogram-scale green synthesis of hierarchical 4A zeolite@CuO (OH) (0 ≤ < 1) nanosheet assemblies core-shell nanoarchitectures with Superb Congo red adsorption performance.

Delicate design of hierarchical nanoarchitectures has become a highly effective strategy to develop novel adsorbents with improved adsorption capacity. Herein, hectogram-scale green fabrication of hierarchical 4A zeolite@CuO (OH) (0 ≤ < 1) nanosheet assemblies core-shell nanoarchitectures (4A-Cu-, was the calcination temperature) with terrific Congo red (CR) dye adsorption performance was achieved through a simple, template-free and surfactant-free hydrothermal approach. A series of characterization techniques, including scanning electron microscopy, transmission electron microscopy, X-ray diffraction and photoelectron spectroscopy demonstrated that all resultant adsorbents featured a core-shell structure with 4A zeolite as core ingredients and CuO (OH) (0 ≤ < 1) nanosheet assemblies as shell components.