Evaluating the tolerability and acceptability of a locally produced alcohol-based handrub and hand hygiene behaviour among health workers in Sierra Leone: a longitudinal hospital-based intervention study.

Background: Alcohol-based handrub (ABHR) is the gold standard for hand hygiene (HH) and is a cornerstone of infection prevention and control (IPC) strategies. However, several factors influence the efficient use of ABHR by health workers. This study evaluated the tolerability and acceptability of a locally produced ABHR product and HH behaviour among health workers.

Deforestation amplifies climate change effects on warming and cloud level rise in African montane forests.

Tropical montane forest ecosystems are pivotal for sustaining biodiversity and essential terrestrial ecosystem services, including the provision of high-quality fresh water. Nonetheless, the impact of montane deforestation and climate change on the capacity of forests to deliver ecosystem services is yet to be fully understood. In this study, we offer observational evidence demonstrating the response of air temperature and cloud base height to deforestation in African montane forests over the last two decades.

Assessment of antimicrobial stewardship programmes and antibiotic use among children admitted to two hospitals in Sierra Leone: a cross-sectional study.

Introduction: Antimicrobial resistance (AMR) is a global public health concern and irrational use of antibiotics in hospitals is a key driver of AMR. Even though it is not preventable, antimicrobial stewardship (AMS) programmes will reduce or slow it down. Research evidence from Sierra Leone has demonstrated the high use of antibiotics in hospitals, but no study has assessed hospital AMS programmes and antibiotic use specifically among children.

Factors impacting water quality and quantity in rapidly expanding urban areas based on the DPSIR model: experiences and challenges from Addis Ababa City, Ethiopia.

Due to the increasing pressures of global change, such as urbanization, climate change, population growth, and socioeconomic changes, cities around the world are facing significant water challenges, both in terms of supply and quality. This emphasizes the need for concerted effort to manage water supplies effectively for sustainable development. The driver, pressure, state, impact, and response (DPSIR) model was applied in this study to determine the underlying causes of Addis Ababa's water supply and quality issues.

The Ripple Effect of Climate Change: Assessing the Impacts on Water Quality and Hydrology in Addis Ababa City (Akaki Catchment).

This research aimed to evaluate the effects of climate change on the hydrology and water quality in the Akaki catchment, which provides water to Addis Ababa, Ethiopia. This was performed using the soil and water assessment tool (SWAT) model and an ensemble of four global climate models under two Shared Socioeconomic Pathways (SSP) emission scenarios from Coupled Model Intercomparison Project Phase 6 (CMIP6). The climate data were downscaled and bias-corrected using the CMhyd tool and calibrated and validated using the SWAT-CUP software package.

Implications of land use/land cover dynamics on urban water quality: Case of Addis Ababa city, Ethiopia.

Water resources are often at the center of urban development but, as the city expands, the environmental pressure on its water resources increases. Therefore, in this study, we looked into how various land uses and changes in land cover affect the water quality in Addis Ababa, Ethiopia. Land use and land cover change maps were generated from 1991 to 2021 at intervals of five years.

Availability of medical abortion medicines in eight countries: a descriptive analysis of key findings and opportunities.

Background: In recent years a growing number of manufacturers and medical abortion products have entered country markets and health systems, with varying degrees of quality and accessibility. An interplay of factors including pharmaceutical regulations, abortion laws, government policies and service delivery guidelines and provider's knowledge and practices influence the availability of medical abortion medicines. We assessed the availability of medical abortion in eight countries to increase understanding among policymakers of the need to improve availability and affordability of quality-assured medical abortion products at regional and national levels.

Regular measurement is essential but insufficient to improve quality of healthcare.

argue that large scale improvements in quality of healthcare require strong change management as well as health information systems that can provide continuous and rapid feedback

The rate and perioperative mortality of caesarean section in Sierra Leone.

Introduction: Sierra Leone has the world's highest maternal mortality, partly due to low access to caesarean section. Limited data are available to guide improvement. In this study, we aimed to analyse the rate and mortality of caesarean sections in the country.

Primary HIV-1 subtype C infection in Ethiopia.

Between 1997 and 2001, 1624 Ethiopian factory workers were enrolled in prospective HIV-1 cohorts in Ethiopia, at Akaki and Wonji towns. HIV-1 seroprevalence at intake was 11.8% (Akaki) and 7.