Time-Domain Blind ICI Compensation in Coherent Optical FBMC/OQAM System.

A blind discrete-cosine-transform-based phase noise compensation (BD-PNC) is proposed to compensate the inter-carrier-interference (ICI) in the coherent optical offset-quadrature amplitude modulation (OQAM)-based filter-bank multicarrier (CO-FBMC/OQAM) transmission system. Since the phase noise sample can be approximated by an expansion of the discrete cosine transform (DCT) in the time-domain, a time-domain compensation model is built for the transmission system. According to the model, phase noise compensation (PNC) depends only on its DCT coefficients.

miR-196 acts as a tumor suppressor in osteosarcoma by targeting HOXA9.

Abnormal expression of microRNAs (miRNAs) has been found in most cancer types. Therefore, the discovery of miRNAs could help us to understand the mechanism of tumor initiation and development. The purpose of this study was to investigate the significance of miR-196 in osteosarcoma (OS) and to identify its target genes.

Inactivation of the Rho-ROCK signaling pathway to promote neurologic recovery after spinal cord injuries in rats.

Background: After injury, axonal regeneration of the adult central nervous system (CNS) is inhibited by myelin-derived growth-suppressing proteins. These axonal growth inhibitory proteins are mediated via activation of Rho, a small GTP-binding protein. The activated form of Rho, which is bound to GTP, is the direct activator of Rho kinase (ROCK) through serial downstream effector proteins to inhibit axonal regeneration.

Recombinant BMP 4/7 fusion protein induces differentiation of bone marrow stem cells.

Bone morphogenetic proteins (BMPs) induce differentiation of mesenchymal cells to cartilage and bone. We cloned BMP4 and BMP7 cDNAs from human placenta and fetal cartilage cells, respectively, and used an Escherichia coli expression system to produce recombinant BMP4 and BMP4/7 proteins. Differentiation of primary cultures of bone marrow stem cells (BMSC) treated with BMP4 or BMP4/7 was evaluated by Von Kossa staining and by determining alkaline phosphatase activity and osteocalcin level.