Publications by authors named "Binod G C"
Article Synopsis
- - Gfi1 is a crucial transcriptional repressor involved in blood cell development, mainly working through its SNAG domain to recruit the histone demethylase LSD1, affecting gene regulation.
- - The study reveals Gfi1's ability to enhance the expression of the Hemgn gene via a specific promoter region, with interactions from transcription factors like Ikaros (which activates Hemgn) and PU.1 (which represses it).
- - Gfi1's upregulation of Hemgn not only occurs through repression of PU.1 but also contributes to Gfi1's protective role against cell death caused by stress, independent of the p53 protein.
Background: is a cardinal source of community- and hospital-acquired infection. HIV infection is a well-recognized risk factor for methicillin-resistant (MRSA) carriage and infection. Intrinsically developed antibiotic resistance has sharply increased the burden of MRSA which is often associated with morbidity and mortality of the patients.
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