Pharmacodynamic studies on the isolated active fraction of Acacia farnesiana (L.) willd.

Background: Acacia farnesiana is a medicinal plant that grows throughout tropical parts of Indian subcontinent, particularly in sandy soils of river beds in Northern India. The objective of the present study was to evaluate the anti-hyperglycemic activity of the extracts using glucose tolerance test. Isolation of an active fraction (AF) from the active extract (water extract) using alcohol precipitation and to get insight to the mechanism of action of the AF of A.

Anti-diabetic activity of active fractions of Stereospermum tetragonum DC and isolation of active principles.

Objectives: To identify the active principles, determine the anti-diabetes activity of fraction of Stereospermum tetragonum root.

Materials And Methods: The efficacy was evaluated in streptozotocin induced type 2 diabetic rats and the anti-hyperglycemic activity was studied by glucose tolerance test. The major active compounds were isolated by solvent fractionation and chromatographic techniques and characterized with spectral data.