Hot tub-associated dermatitis due to Pseudomonas aeruginosa. Case report and review of the literature.

A healthy, 27-year-old man had development of a maculopapular, pustular rash due to Pseudomonas aeruginosa, serotype 0:4, after bathing in a hot tub. Two persons sharing the same tub manifested a similar rash. In the first patient, the eruption was distributed mainly over the back, buttocks, and upper arms, appearing abruptly within 24 to 72 hours after use of the hot tub.

Drug-induced toxic epidermal necrolysis in children. Report of two cases.

Two cases of toxic epidermal necrolysis occurring in children are presented herein. In both, multiple drugs were administered before the onset of the skin eruption. Cultures for staphylococcus were negative.

Scleroderma, eosinophilia, and diffuse fasciitis.

Skin induration without internal organ involvement, blood and tissue eosinophilla, and fascilitis are features of diffuse fascilitis. However, cellular infiltrates (lymphocytes, plasma cells, and eosinophils) may also be present in the dermis, fat, and muscle. Blood eosinophilia (mild and transient) and skin eosinophilia were observed in about 20% of patients with systemic and localized scleroderma.

Pityriasis rubra pilaris responding to aminonicotinamide.

A 32-year-old man with pityriasis rubra pilaris diagnosed by clinical appearance and histologic examination was treated with 1% aminonicotinamide cream applied once daily. Improvement was noted within four days, and almost complete clearing occurred after two weeks of therapy. No side-effects were noted.

Failure of dimethyl sulfoxide in the treatment of scleroderma.

Nineteen patients with systemic scleroderma and five with localized scleroderma were treated with topical dimethyl sulfoxide by painting and immersion techniques. Partial control was obtained by using a very low concentration (5%) on one side when involvement was symmetrical. Duration of treatment ranged from 3 to 15 months.

Hypoglycemia and ventricular tachycardia due to adenocarcinoma of the stomach.

We report the first case of adenocarcinoma of the stomach associated with severe hypoglycemia. Accompanying the profound hypoglycemia, as low as 5 mg per cent by the orthotoluidine method, were multiple episodes of ventricular tachycardia which were abolished by glucose infusion. Following surgical excision of a hemorrhagic portion of the tumor, normoglycemia levels were achieved and ventricular irritability was no longer present.