Publications by authors named "Biniam Melese Bekele"

Article Synopsis
  • Heart transplantation enhances survival and quality of life for patients with end-stage heart failure due to cardiomyopathies, which often have genetic roots.
  • A study evaluated 39 patients for muscle function and quality of life, using interviews and whole-exome sequencing for those with muscle weakness.
  • Results showed that 17.9% of patients experienced new muscle weakness, with genetic testing identifying several pathogenic variants in some, suggesting a need for genetic assessment and neurological evaluation in heart transplant candidates.
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Purpose: This longitudinal study aimed to disentangle the impact of chemotherapy on fatigue and hypothetically associated functional brain network alterations.

Methods: In total, 34 breast cancer patients treated with chemotherapy (BCC +), 32 patients not treated with chemotherapy (BCC -), and 35 non-cancer controls (NC) were included. Fatigue was assessed using the EORTC QLQ-C30 fatigue subscale at two time points: baseline (T1) and six months after completion of chemotherapy or matched intervals (T2).

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