Publications by authors named "Binh Nguyen Thi Thanh"

Article Synopsis
  • Hydrophobicity plays a key role in how amphipathic antimicrobial peptides interact with microbial pathogens, but it's influenced by other structural factors like peptide length and charge.
  • The study compares three similar natural antimicrobial peptides—mastoparan C, mastoparan-AF, and mastoparan L—with varying levels of hydrophobicity, finding that mastoparan C has the highest hydrophobicity and helical content, leading to strong hemolytic activity.
  • It concludes that an optimal level of hydrophobicity improves antimicrobial effectiveness while reducing harmful hemolytic activity, rather than simply maximizing hydrophobicity.
View Article and Find Full Text PDF

The linear undecapeptide BP52 was previously reported to have antibacterial activity against phytopathogenic bacteria species. Due to the structural similarities to naturally occurring cationic helical antimicrobial peptides, it was speculated that this peptide could potentially target microbial pathogens and cancer cells found in mammals. Consequently, this study aims to further investigate the structural and biological properties of this peptide.

View Article and Find Full Text PDF

Interprofessional education is acknowledged as an efficacious strategy for fostering collaboration among healthcare professionals, especially in developing countries where interdisciplinarity and cooperation among healthcare practitioners are notably deficient. The present study aimed to investigate the readiness among medical, pharmacy, public health, and nursing faculties for development of an IPE curriculum at a university in Vietnam. Employing a quantitative approach, the revised version of the Readiness for Interprofessional Learning Scale (RIPLS) questionnaire, comprising 19 items, was utilized to gather data from sixty-nine lecturers, including 26 medicine, 23 pharmacy, 11 public health, and 9 nursing faculties.

View Article and Find Full Text PDF

The ability of amphipathic peptides to arrange themselves in aqueous solutions, known as self-assembly, has been found to reduce the effectiveness of these peptides in interacting with cell membranes. Therefore, minimizing their tendency to self-assemble could be a potential strategy for enhancing the pharmacological properties of antimicrobial peptides (AMPs). To explore this idea, this study prepared a series of natural peptides () with increased net charge and hydrophilicity via alanine-to-lysine substitution and investigated the impact on the biological activity.

View Article and Find Full Text PDF

Background: Heavy metal contamination and related risks for the environment and human health are matters of increasing concern.

Methods: The levels of 4 heavy metals (Cr, Cd, Pb, and As) were evaluated in 2 water types (surface and well), 4 types of seafood (tiger shrimp, stuffed snail, snake-head fish, and catfish), and 27 types of vegetables (12 leafy vegetables, 4 pea plants, 4 tuber vegetables, and 7 herbs) that are commonly consumed in northern coastal communes located in Vietnam. Atomic absorption spectrometry was employed for quantification.

View Article and Find Full Text PDF

Background: Dementia poses a serious threat to the wellbeing of the elderly. In the context of the rapidly ageing population of Vietnam however, little is known about the prevalence of symptoms and other related factors. This study aims to detect the prevalence of cognitive symptoms of dementia in the elderly in Vietnam as well as other associated factors.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed 135 stomach samples from patients with gastrointestinal issues and healthy controls to investigate Helicobacter pylori and Candida infections.
  • Candida krusei was present in 20% of bleeding patients, 52% of ulcer patients, and 100% of gastritis patients, while H. pylori was found in 82%, 35%, and 30% of these groups, respectively.
  • No Candida krusei was found in samples from healthy controls, indicating a potential association with gastrointestinal diseases.
View Article and Find Full Text PDF

Personal exposure to benzene of selected population groups, and impacts of traffic on commuters in Ho Chi Minh City were investigated. The study was carried out in June, July and November 2010. The preliminary data showed that on average, personal exposure to benzene for non-occupational people in Ho Chi Minh is ~18 μg/m(3) and most of the exposure is due to commuting.

View Article and Find Full Text PDF

A new home-made diffusive bag-type passive sampler called Lanwatsu was developed for benzene, toluene, ethylbenzene and xylene monitoring in roadside air. The passive samplers were outdoor validated and deployed together with two commercial passive samplers, Ultra I SKC Inc. and Radiello, for daily roadside air monitoring in East Asian cities including HoChiMinh, Hanoi, Cantho, Danang, Vungtau, Hue (Vietnam), Kuala Lumpur (Malaysia), Kyoto, Osaka (Japan), Nanjing (China) and Singapore in 2011.

View Article and Find Full Text PDF