Multi-omics analysis revealed the role of CCT2 in the induction of autophagy in Alzheimer's disease.

() is essential in various neurodegenerative diseases, albeit its role in the pathogenesis of Alzheimer's disease (AD) remains elusive. This study aimed to evaluate the role of in Alzheimer's disease. First, bioinformatics database analysis revealed that was significantly downregulated in patients with Alzheimer's disease and associated with autophagic clearance of β-amyloid.