Cypate-loaded hollow mesoporous Prussian blue nanoparticle/hydrogel system for efficient photodynamic therapy/photothermal therapy dual-modal antibacterial therapy.

Infectious diseases caused by pathogenic microorganisms are a significant burden on public health and the economic stability of societies all over the world. The appearance of drug-resistant bacteria has severely blocked the effectiveness of conventional antibiotics. Therefore, developing novel antibiotic-free strategies to combat bacteria holds huge potential for maximizing validity and minimizing the risk of enhancing bacterial resistance.

Near-infrared spectroscopy combined with pattern recognition algorithms to quickly classify raisins.

With the development of commodity economy, the emergence of fake and shoddy raisin has seriously harmed the interests of consumers and enterprises. To deal with this problem, a classification method combining near-infrared spectroscopy and pattern recognition algorithms were proposed for adulterated raisins. In this study, the experiment was performed by three kinds of raisins in Xinjiang (Hongxiangfei, Manaiti, Munage).

Raman spectroscopy combined with machine learning algorithms to detect adulterated Suichang native honey.

Zhejiang Suichang native honey, which is included in the list of China's National Geographical Indication Agricultural Products Protection Project, is very popular. This study proposes a method of Raman spectroscopy combined with machine learning algorithms to accurately detect low-concentration adulterated Suichang native honey. In this study, the native honey collected by local beekeepers in Suichang was selected for adulteration detection.

In-capillary probing QDs and HAT tag self-assembly and displacement using Förster resonance energy transfer.

HAT tag, a natural His affinity tag, is one of the most popular fusion tags. However, HAT tag containing three positive charges limited its self-assembly with quantum dots (QDs). Herein, ATTO 590-labeled HAT peptide was synthesized to self-assemble with QDs inside the capillary.

Online probing quantum dots and engineered enzyme self-assembly in a nanoliter scale.

Nanoparticles provide significantly enhanced binding characteristics. However, fast online probing of the self-assembly process remains hard to achieve in practice. Herein, we report a fluorescence coupled CE method for probing the self-assembly events between quantum dots (QDs) and engineered Jumonji domain-containing protein 6 (Jmjd6) enzyme.

Capillary electrophoretic studies on quantum dots and histidine appended peptides self-assembly.

Herein, we designed four peptides appended with different numbers of histidine (Hisn -peptide). We launched a systematic investigation on quantum dots (QDs) and Hisn -peptide self-assembly in solution using fluorescence coupled CE (CE-FL). The results indicated that CE-FL was a powerful method to probe how ligands interaction on the surface of nanoparticles.