Enhancing hospital protection measures reduces frontline medical workers' stress during the pandemic.

Frontline medical workers (FMWs) faced high stress levels in frontline clinics during the COVID-19 pandemic. This study aims to alleviate FMWs' psychological stress by enhancing protection measures, which includes refining the selection process, improving protective measures for their work in frontline clinics, and determining the appropriate time for evacuation. A Chinese-language-version stress questionnaire, covering stress-related issues and sociodemographic characteristics, was administered to FMWs in Shanghai during the COVID-19 pandemic in 2022, yielding 107 valid responses.

Hairy Cell Leukemia Following Acute Myeloid Leukemia, Concomitant or Secondary?

A 62-year-old man diagnosed with acute myeloid leukemia (AML) showed limited responses to two courses of azacitidine (AZA)+Venetoclax (VEN) therapy. Twenty days after being transferred to our hospital, flow cytometry with broad antigen coverage and mutation analysis confirmed the presence of a second malignancy, hairy cell leukemia (HCL). Following haploidentical combined umbilical cord blood transplantation, the patient achieved complete remission (CR) for both AML and HCL.

An ionically cross-linked composite hydrogel electrolyte based on natural biomacromolecules for sustainable zinc-ion batteries.

Zinc-ion batteries (ZIBs) are regarded as promising power sources for flexible and biocompatible devices due to their good sustainability and high intrinsic safety. However, their applications have been hindered by the issues of uncontrolled Zn dendrite growth and severe water-induced side reactions in conventional liquid electrolytes. Herein, an ionically cross-linked composite hydrogel electrolyte based on natural biomacromolecules, including iota-carrageenan and sodium alginate, is designed to promote highly efficient and reversible Zn plating/stripping.

Dual water-electricity cooperation improves economic benefits and water equality in the Lancang-Mekong River Basin.

Transboundary river cooperation provides an effective pathway to maintain regional security and sustainable development; however, its implementation is a pressing and prominent concern due to lack of appropriate compensation measures and effective incentive strategies. Here we develop a dual water-electricity cooperation (DWEC) framework that combines water and electricity trading to meet the often-conflicting demands of participating countries. The results from the Lancang-Mekong River Basin reveal that substantial benefits in both economic and social aspects can be achieved through coupling regional water and electricity trades.

Development of a recurrent spatiotemporal deep-learning method coupled with data fusion for correction of hourly ozone forecasts.

Ambient ozone (O) predictions can be very challenging mainly due to the highly nonlinear photochemistry among its precursors, and meteorological conditions and regional transport can further complicate the O formation processes. The emission-based chemical transport models (CTM) are broadly used to predict O formation, but they may deviate from observations due to input uncertainties such as emissions and meteorological data, in addition to the treatment of O nonlinear chemistry. In this study, an innovative recurrent spatiotemporal deep-learning (RSDL) method with model-monitor coupled convolutional recurrent neural networks (ConvRNN) has been developed to improve O predictions of CTM.

Predictive value of fetal echocardiographic parameters in surgical strategy for Tetralogy of Fallot.

Objectives: This study aimed to evaluate whether fetal echocardiographic parameters were predictive of the postnatal surgical treatment required for fetuses with Tetralogy of Fallot (TOF).

Methods: The fetal echocardiographic and postnatal clinical data of all cases of prenatal TOF at Xinhua Hospital from 2016 to 2020 were reviewed. Patients were categorized based on the operation type, and cardiac parameters were compared between groups.

[Genetic analysis of a case of B-acute lymphoblastic leukaemia with double Philadelphia chromosomes and double derivative chromosome 9s].

Objective: To explore the genetic basis for a rare case of acute B-lymphocytic leukemia (B-ALL) with double Philadelphia chromosomes (Ph) and double derivative chromosome 9s [der(9)].

Methods: A patient with double Ph and double der(9) B-ALL who presented at Shanghai Zhaxin Intergrated Traditional Chinese and Western Medicine Hospital in June 2020 was selected as the subject. Bone marrow morphology, flow cytometry, G-banding karyotyping, fluorescence in situ hybridization (FISH), genetic testing and chromosomal microarray analysis (CMA) were used to analyze bone marrow samples from the patient at various stages.

Tuning Zn coordination tunnel by hierarchical gel electrolyte for dendrite-free zinc anode.

Aqueous zinc-ion batteries (ZIBs) are perceived as one of the most upcoming grid-scale storage systems. However, the issues of electrode dissolution, dendrite formation, and corrosion in traditional liquid electrolytes have plagued its progress. In this work, Zn dendrite growth and side reactions are effectively suppressed by a highly-confined tannic acid (TA) modified sodium alginate (SA) composite gel electrolyte (TA-SA).

Novel compound heterozygous mutations in a familial case of primary ciliary dyskinesia.

Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by motile ciliary dysfunction and impaired ultrastructure. Despite numerous studies, the genetic basis for about 30% of PCD cases remains to be elucidated. Here, we present the identification and functional analysis of two novel mutations in the gene encoding coiled-coil domain-containing protein 40 (CCDC40), which are found in a familial case of PCD.

Different Pattern of Cardiovascular Impairment in Methylmalonic Acidaemia Subtypes.

Methylmalonic acidaemia (MMA) has been reported to be associated with cardiovascular involvement, especially for the combined type with homocystinuria. We have screened 80 control subjects and 99 MMA patients (23 isolated type and 76 combined type) using electrocardiograph and echocardiography. 32 cases (34%) of ECG changes were found including sinus tachycardia ( = 11), prolonged QTc interval ( = 1), I-degree atrioventricular block ( = 1), left axis deviation ( = 5) and T wave change ( = 14).

A landscape of circulating long non-coding RNA (lncRNA) expression profile and the predictive value of candidate lncRNAs for disease risk of knee osteoarthritis.

Background: This study aimed to investigate the plasma long non-coding RNA (lncRNA) expression profile in knee osteoarthritis (KOA) patients and the value of candidate lncRNAs for predicting KOA risk.

Methods: Plasma was obtained for RNA sequencing (RNA-seq) in eight KOA patients and eight healthy controls (Ctrls). Ten candidate lncRNAs were then selected from the differentially expressed (DE) lncRNAs according to the rank of absolute value of Log (fold change).

Mechanisms for ·[Formula: see text] and ·OH Production on Flowerlike BiVO Photocatalysis Based on Electron Spin Resonance.

Many studies have focused on the use of BiVO as a photocatalyst, but few have investigated the production of free radicals during the photocatalytic process. Following synthesis of flowerlike BiVO and characterization by X-ray diffraction (XRD), Raman spectroscopy, Scanning electron microscopy (SEM) Scanning electron microscopy (EDX), UV-Vis and XPS, we successfully prepared BiVO. Then we used electron spin resonance (ESR) to determine the production and degradation of individual active free radicals, including the superoxide radical (·[Formula: see text]) and the hydroxyl radical (·OH).

Ultrahigh gas storage both at low and high pressures in KOH-activated carbonized porous aromatic frameworks.

The carbonized PAF-1 derivatives formed by high-temperature KOH activation showed a unique bimodal microporous structure located at 0.6 nm and 1.2 nm and high surface area.