Publications by authors named "Bingxuan Jiao"

Article Synopsis
  • * In a study of 550 patients, we found a much higher prevalence of NAFLD (76.5%) in those with cerebrovascular symptoms compared to those without (9.8%).
  • * Our analysis indicated that even after considering other health factors, NAFLD remained strongly correlated with cerebrovascular symptoms, suggesting it could be a key predictor of symptomatic carotid plaques and related issues.
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Article Synopsis
  • Pneumonic-type primary pulmonary lymphoma (PPL) is frequently misidentified as pneumonia, necessitating accurate diagnosis due to differing treatment requirements.!* -
  • A study analyzed 227 patients with either pneumonic-type PPL or pneumonia, comparing clinical symptoms and CT imaging features to identify distinguishing factors.!* -
  • Key findings indicated that patients with pneumonia exhibited more common symptoms like fever and sputum, while specific imaging features like bronchiectasis and halo sign were more associated with pneumonic-type PPL, highlighting the need for precise diagnostic techniques.!*
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Rationale And Introduction: It is of significance to assess the severity and predict the mortality of patients with connective tissue disease-associated interstitial lung disease (CTD-ILD). In this double-center retrospective study, we developed and validated a radiomics nomogram for clinical management by using the ILD-GAP (gender, age, and pulmonary physiology) index system.

Materials And Methods: Patients with CTD-ILD were staged using the ILD-GAP index system.

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The endoplasmic reticulum (ER) is a membranous network within cells that is important for several cellular functions including translation and folding of secretory and membrane proteins, lipid biogenesis and sequestration of Ca2+. Disruption of ER structure might affect the normal physiology of the cells. In yeast, expansion of the ER is observed under unfolded protein response (UPR) and subsequently induces autophagy initiated from the ER.

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Bcl-2, which belongs to the Bcl-2 family, is frequently overexpressed in various types of cancer cells and contributes to drug resistance. However, the function of Bcl-2 in cisplatin resistance in human ovarian cancer cells is not fully understood. In this study, we found that the pharmacological inhibitor ABT737 or genetic knockdown of Bcl-2 increased cisplatin cytotoxicity in cisplatin-resistant ovarian cancer cells.

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