Synthesis of 1,4-benzodioxepines electrochemical oxyselenenylation of 2--tethered alkenyl phenylmethanol and diselenides.

A highly efficient methodology has been developed for the synthesis of 1,4-benzodioxepines through electrochemical oxyselenenylation of 2--tethered alkenyl phenylmethanol and diselenides under external oxidant-free conditions at room temperature. Experimental evidence supports this transformation to occur a radical mechanism.

Porous aromatic frameworks with high Pd nanoparticles loading as efficient catalysts for the Suzuki coupling reaction.

The development of efficient and recyclable heterogeneous Pd catalysts is an area of continuing attention due to their critical applications in organic synthesis and pharmaceutical production. In this study, two novel heterogeneous catalysts Pd@PAF-182 and Pd@PAF-183 were prepared by the immobilization/NaBH reduction of PdCl on hydrophilic cationic porous aromatic frameworks (PAF-182 and PAF-183), which were synthesized via a Yamamoto-type Ullmann coupling reaction from the corresponding aryl quaternary phosphonium salt monomer. Characterization by powder X-ray diffraction (PXRD), solid-state Cross-Polarization Magic-Angle-Spinning Nuclear Magnetic Resonance (CP/MAS NMR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) established the structures of the as-prepared catalysts.

Developments in the construction of cyclopropanols.

The ring-opening of cyclopropanols is one of the most active areas of research and it has been well documented in recent years owing to subsequent coupling with various partners, thus providing the facile syntheses of a large number of multifunctional compounds that may otherwise be difficult to access. Evidently, the useful cascade reaction requires easy access to diversely functionalized cyclopropanol substrates. However, developments in the construction of cyclopropanols have not received adequate attention.

Additive Tuned Selective Synthesis of Bicyclo[3.3.0]octan-1-ols and Bicyclo[3.1.0]hexan-1-ols Mediated by AllylSmBr.

The selective construction of bicyclo[3.3.0]octan-1-ols and bicyclo[3.

Alternative Sm(II) Species-Mediated Cascade Coupling/Cyclization for the Synthesis of Oxobicyclo[3.1.0]hexane-1-ols.

The allylSmBr/HMPA/MsOH system has been found to be an efficient reagent for the "ester-alkene" coupling/cyclization cascade of readily available α-allyloxy esters. Oxobicyclo[3.1.

SmI-mediated reductive cyclization of β-arylthio ketones: a facile and diastereoselective synthesis of thiochroman derivatives.

SmI-mediated reductive cyclization of β-arylthio ketones to generate thiochroman derivatives is not a generally observed process and the reported examples are limited to geminal disubstitution in the substrates. The results of the current study show that the cyclization also occurs when other substitution patterns are present, affording a general approach to dihydrothiochroman-ols in good yields and high degrees of diastereoselectivity. Besides, the halogen substitution on β-aryl is tolerated in most cases here although reductive dehalogenation has been reported to predominate in the reductive cyclization process.