Systems biochemical responses of rats to Kansui and vinegar-processed Kansui exposure by integrated metabonomics.

Ethnopharmacological Relevance: The dried root of Kansui (Euphorbia kansui L.) is an effective and commonly used traditional Chinese medicine. Even so, Kansui cannot be satisfactorily applied clinically because of toxic side effects.

1H NMR-based metabonomics study of the urinary biochemical changes in Kansui treated rat.

Ethnopharmacological Relevance: The dried root of Kansui (Euphorbia kansui L.) is a commonly used and effective traditional Chinese medicine (TCM).

Aim Of The Study: We combined the urinary metabolites alteration and traditional assays of Kansui-induced rats to discuss the mechanism of toxicity of Kansui.