Publications by authors named "Bingshuo Liu"

Article Synopsis
  • - This study investigates the adverse drug events (ADEs) linked to TNF-α inhibitors (TNFis) used in rheumatoid arthritis (RA) patients, pulling data from the FDA's reporting system to enhance clinical understanding.
  • - Four common ADEs among TNFis are identified (pulmonary tuberculosis, infections, hypersensitivity, and herpes zoster), but each TNFi also has unique ADEs: Adalimumab has the highest with 63 unique events, while etanercept has 180 unique ADEs.
  • - The research highlights the need for careful medication selection by clinicians, especially for RA patients with existing malignancies, due to the variety of common and unique ADEs linked to different TNFis.
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Objective: After the unprecedented coronavirus disease 2019 (COVID-19) outbreak, the health status of the general population has suffered a huge threat, and the mental health of front-line healthcare providers has also encountered great challenges. Therefore, this study aims to: (1) investigate the prevalence and influencing factors of post-traumatic stress disorder (PTSD) among healthcare providers, and (2) verify the moderating role of self-efficacy in the influence of PTSD on mental health.

Methods: A cross-sectional study was conducted using an online survey of 1993 participants.

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Objectives: To explore the correlations among social isolation and symptoms of anxiety and depression among patients with breast cancer in China and to further verify the mediating role of social support in social isolation and symptoms of depression or anxiety.

Design: A cross-sectional survey.

Settings: The cluster sampling method was conducted for 456 female inpatients diagnosed with breast cancer at the Tumor Hospital Affiliated of Harbin Medical University from April 2019-September 2019.

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Black currant extract (BCE) is rich in polyphenols and can induce apoptosis in various cancer cells, but the molecular mechanism by which BCE induces cancer cell apoptosis has not been reported. The aim of this work was to elucidate the antitumor effect of BCE and the signal transduction pathways involved. MTT test results revealed that the viability of MKN-45 and TE-1 cells treated with BCE gradually decreased in a concentration-dependent manner, with significant effects achieved after 12 h of treatment.

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