Enhancing Clinical Decision Making by Predicting Readmission Risk in Patients With Heart Failure Using Machine Learning: Predictive Model Development Study.

Background: Patients with heart failure frequently face the possibility of rehospitalization following an initial hospital stay, placing a significant burden on both patients and health care systems. Accurate predictive tools are crucial for guiding clinical decision-making and optimizing patient care. However, the effectiveness of existing models tailored specifically to the Chinese population is still limited.

Research Progress of Vagal Nerve Regulation Mechanism in Acupuncture Treatment of Atrial Fibrillation.

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. It has a high prevalence and poor prognosis. The application of antiarrhythmic drugs and even surgery cannot completely treat the disease, and there are many sequelae.

New Adsorption Materials for Deep Desulfurization of Fuel Oil.

In recent years, due to the rapid growth of mankind's demand for energy, harmful gases (SOx) produced by the combustion of sulfur-containing compounds in fuel oil have caused serious problems to the ecological environment and human health. Therefore, in order to solve this hidden danger from the source, countries around the world have created increasingly strict standards for the sulfur content in fuel. Adsorption desulfurization technology has attracted wide attention due to its advantages of energy saving and low operating cost.

Efficacy of Fire-Needle Therapy in Improving Neurological Function Following Cerebral Infarction and Its Effect on Intestinal Flora Metabolites.

Objective: This study was to investigate the mechanism of action and clinical efficacy of fire-needle therapy in improving neurological function in patients with acute cerebral infarction (identified as a wind-phlegm-blood stasis syndrome in traditional Chinese medicine).

Methods: We included patients diagnosed with acute cerebral infarction (wind-phlegm-blood stasis syndrome) admitted to the Encephalopathy and Acupuncture Center of the Second Affiliated Hospital of Tianjin University of Chinese Medicine. We randomly allocated them into the treatment and control groups, with 45 cases in each group.

Advances in Emerging Catalytic Materials for the Conversion of Carbon Dioxide.

The use of fossil fuels leads to significant CO emissions, thus highlighting the importance for investigating the utilization of CO for generating high-value chemical products toward achieving the dual-carbon goal. CO can be efficiently used in synthesizing valuable organic compounds through C-C, C-O, C-H, and C-N bond construction, with reduction technologies effectively converting CO to organic carbon sources. Therefore, the research in developing environmentally friendly catalysts for efficient and renewable CO conversion holds great importance.

Progress in the Synthesis Process and Electrocatalytic Application of MXene Materials.

With their rich surface chemistry, high electrical conductivity, variable bandgap, and thermal stability, 2D materials have been developed for effective electrochemical energy conversion systems over the past decade. Due to the diversity brought about by the use of transition metals and C/N pairings, the 2D material MXene has found excellent applications in many fields. Among the various applications, many breakthroughs have been made in electrocatalytic applications.

Insight into the enhancement effect of amino functionalized carbon nanotubes on the HS removal performance of nanofluid system.

By constructing nanofluid system, trace functionalized nanoparticles can significantly enhance the absorption performance of basic liquid. In this work, amino functionalized carbon nanotubes (ACNTs) and carbon nanotubes (CNTs) were introduced into alkaline deep eutectic solvents to build nanofluid systems and used for the dynamic absorption of HS. The experiment results showed that the introduction of nanoparticles can significantly enhance the HS removal performance of original liquid.

Efficient Diesel Desulfurization by Novel Amphiphilic Polyoxometalate-Based Hybrid Catalyst at Room Temperature.

Amphiphilic hybrid catalysts were prepared by modifying [SMoO] with tetrabutylammonium bromide (TBAB), 1-butyl-3-methylimidazole bromide (BMIMBr) and octadecyl trimethyl ammonium bromide (ODAB), respectively. The prepared catalysts were characterized by IR, XRD, SEM, TG and XPS. The desulfurization performance of the catalysts was investigated in model oil and actual diesel using hydrogen peroxide (HO) as an oxidant and acetonitrile as an extractant.

Photocatalytic Activities of g-CN (CN) Treated with Nitric Acid Vapor for the Degradation of Pollutants in Wastewater.

In this article, we reported a novel setup treatment using nitric acid vapor to treat g-CN (CN). By treatment with nitric acid vapour, the basic structure of the CN has not been destroyed. These adoptive treatments enhanced the photocatalytic performance of CN and were reflected in the elimination of rhodamine B (RhB) as well as tetracycline hydrochloride (TC).

Ultrasonics methodology for defect and stress detection of in-serviced T-shaped R-zone components.

The T-shaped R-zone component widely exists in aerospace and satellite communication area, such as supporting structure under the wing skin and the mechanical supporting frame of the satellite large load-bearing high-precision test platform, which seriously affects the performance and the safety of the aircraft and the satellite. In this paper, the overall process of ultrasonics methodology of T-shaped R-zone components is proposed, systematically investigated and experimentally verified. The detection of the defect and the stress is respectively realized based on the synthetic aperture total focusing method and the Mohr's stress circle theory with the aid of the linear phased array probe and the longitudinal wave along the stress propagation direction.

Glycinebetaine mitigates tomato chilling stress by maintaining high-cyclic electron flow rate of photosystem I and stability of photosystem II.

Glycinebetaine alleviates chilling stress by protecting photosystems I and II in BADH-transgenic and GB-treated tomato plants, which can be an effective strategy for improving crop chilling tolerance. Tomato (Solanum lycopersicum) is one of the most cultivated vegetables in the world, but is highly susceptible to chilling stress and does not naturally accumulate glycinebetaine (GB), one of the most effective stress protectants. The protective mechanisms of GB on photosystem I (PSI) and photosystem II (PSII) against chilling stress, however, remain poorly understood.

Rich polymorphism in nicotinamide revealed by melt crystallization and crystal structure prediction.

Overprediction is a major limitation of current crystal structure prediction (CSP) methods. It is difficult to determine whether computer-predicted polymorphic structures are artefacts of the calculation model or are polymorphs that have not yet been found. Here, we reported the well-known vitamin nicotinamide (NIC) to be a highly polymorphic compound with nine solved single-crystal structures determined by performing melt crystallization.

Active fluidic chip produced using 3D-printing for combinatorial therapeutic screening on liver tumor spheroid.

Known for their capabilities in automated fluid manipulation, microfluidic devices integrated with pneumatic valves are broadly used for researches in life science and clinical practice. The application is, however, hindered by the high cost and overly complex fabrication procedure. Here, we present an approach for fabricating molds of active fluidic devices using a benchtop 3D printer and a simple 2-step protocol (i.

Synthesis and evaluation of bi-functional 7-hydroxycoumarin platinum(IV) complexes as antitumor agents.

A series of bi-functional 7-hydroxycoumarin platinum(IV) complexes were synthesized, characterized, and evaluated for antitumor activities. The 7-hydroxycoumarin platinum(IV) complexes display moderate to effective antitumor activities toward the tested cell lines and show much potential in overcoming drug resistance of platinum(II) drugs. In reducing microenvironment, the title compounds could be reduced to platinum(II) complex accompanied with two equivalents of coumarin units.

Liver Tumor Spheroid Reconstitution for Testing Mitochondrial Targeted Magnetic Hyperthermia Treatment.

Mitochondria-targeting nanotherapy receives great attention these days for its capacity in disrupting mitochondria function and inducing tumor cell apoptosis through external magnetic and optical stimulations. However, the effect is significantly diminished when applied to animal models. The key factors include environmental complexity in vivo and intrinsic protective features of tumor tissues.

Development of a series of 4-hydroxycoumarin platinum(IV) hybrids as antitumor agents: Synthesis, biological evaluation and action mechanism investigation.

A series of new 4-hydroxycoumarin platinum(IV) complexes were designed, synthesized and evaluated as antitumor agents. All the title compounds display moderate to effective antitumor activities toward the tested cell lines and two prominent compounds were screened out with activities comparable to cisplatin and oxaliplatin. The mechanism investigation demonstrates that the platinum(IV) compounds could be reduced to bivalence and exert significant genotoxicity to tumor cells.

Design and synthesis of a new series of low toxic naphthalimide platinum(IV) antitumor complexes with dual DNA damage mechanism.

Naphthalimide platinum(IV) antitumor complexes with potential dual DNA damage mechanism were designed, synthesized and evaluated for antitumor activities. The incorporation of DNA targeted naphthalimide group to the platinum(IV) system exerts much positive impacts on their antitumor efficacy. The mechanism research reveals that the title compounds could interact with dsDNA in platinum(IV) form via the naphthalimide group and cause DNA lesion.

Polymer-lipid hybrid anti-HER2 nanoparticles for targeted salinomycin delivery to HER2-positive breast cancer stem cells and cancer cells.

Purpose: Breast cancer stem cells (CSCs) are responsible for the initiation, recurrence, and metastasis of breast cancer. Sufficient evidence has established that breast cancer cells can spontaneously turn into breast CSCs. Thus, it is essential to simultaneously target breast CSCs and cancer cells to maximize the efficacy of breast cancer therapy.

Competitive binding of (-)-epigallocatechin-3-gallate and 5-fluorouracil to human serum albumin: A fluorescence and circular dichroism study.

Combination therapy with more than one therapeutic agent can improve therapeutic efficiency and decrease drug resistance. In this study, the interactions of human serum albumin (HSA) with individual or combined anticancer drugs, (-)-epigallocatechin-3-gallate (EGCG) and 5-fluorouracil (FU), were investigated by fluorescence and circular dichroism (CD) spectroscopy. The results demonstrated that the interaction of EGCG or FU with HSA is a process of static quenching and EGCG formed a more stable complex.

Facile Fabrication of Bi2WO6/Ag2S Heterostructure with Enhanced Visible-Light-Driven Photocatalytic Performances.

In this report, a novel photocatalyst based on Bi2WO6/Ag2S heterostructures was prepared by a 3-mercaptopropionic acid (MPA)-assisted route at room temperature. Compared to bare Bi2WO6 and Ag2S nanoparticles, the as-formed Bi2WO6/Ag2S heterostructures exhibit enhanced photocatalytic activity for the degradation of rhodamine B (Rh B) under visible-light irradiation. This kind of enhancement in the photocatalytic activity is considered to be the synergistic effects of both the effective electron-hole separation and expansion of the light-absorption range.

Improved stability of (+)-catechin and (-)-epicatechin by complexing with hydroxypropyl-β-cyclodextrin: Effect of pH, temperature and configuration.

The stability and bioavailability of catechins, a kind of tea polyphenols with health benefit, could be improved by complexing with cyclodextrins. The aim of this study was to investigate the complexation of two geometrical isomers, (+)-catechin and (-)-epicatechin, with hydroxypropyl-β-cyclodextrin (HP-β-CD) in tris-HCl buffer solutions at pH 6.8-8.

[Surgical treatment for primary papillary thyroid cancer: a Meta-analysis].

Objective: To assess and compare the two procedures, total thyroidectomy (TT) and partial thyroidectomy (PT), for papillary thyroid cancer in terms of associated injuries, postoperative complication, recurrence rate and survival, so as to provide a reference and basis for surgical procedure option of this disease.

Method: Strictly specified into the exclusion criteria, the combination of computer retrieval and manual retrieval and retrieval systems such as CNKI, Wang Fan, PubMed, central, CBM database. Total thyroidectomy and partial thyroidectomy for the treatment of patients with thyroid papillary cancer related literature were compared, with the retrieval time until December 31, 2013.

[Echinococcus granulosus infection in dogs and livestock from Xinjiang production and construction corps].

The prevalence of Echinococcus granulosus infection in dogs and livestock was investigated in Xinjiang Production and Construction Corps by stratified random sampling. A total of 5 391 dog feces were detected by double antibody sandwich ELISA, and the positive rate of dog coproantigen was 0.69% (37/5 391).

Improved solubility and stability of 7-hydroxy-4-methylcoumarin at different temperatures and pH values through complexation with sulfobutyl ether-β-cyclodextrin.

The inclusion complex of 7-hydroxy-4-methylcoumarin (7H4MC) with sulfobutyl ether-β-cyclodextrin (SBE-β-CD) was investigated by means of UV-vis, circular dichroism and (1)H NMR spectroscopy in phosphate buffer solutions at different temperatures and pH values. The stoichiometric ratio of the complexation was found to be 1:1 and the stability constants (KC) were estimated from phase solubility analysis. The thermodynamic parameters of standard Gibbs free energy change, ΔG(o), enthalpy change, ΔH(o), and entropy change, ΔS(o), for the complexation process were obtained by using the van't Hoff equation and Gibbs-Helmholtz equation.

Effect of pH on the complexation of kaempferol-4'-glucoside with three β-cyclodextrin derivatives: isothermal titration calorimetry and spectroscopy study.

The utilization of kaempferol and its glycosides in food and pharmaceutical industries could be improved by the formation of inclusion complexes with cyclodextrins at different pH. This study explores the complexation of kaempferol-4'-glucoside with sulfobutyl ether-β-cyclodextrin (SBE-β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD), and methylated-β-cyclodextrin (M-β-CD) in phosphate buffer solutions of different pH using isothermal titration calorimetry, UV-vis absorption and proton nuclear magnetic resonance spectroscopy at 298.2 K.