Publications by authors named "Bingqing Gao"
Article Synopsis
- Cisplatin (DDP) is an effective treatment for advanced ovarian cancer but faces issues like resistance and toxicity; traditional Chinese medicines (TCMs), specifically the herb pair Scutellaria barbata D.Don and Hedyotis diffusa Willd (SB-HD), are being explored for their potential to enhance DDP's effectiveness.
- In laboratory studies, a 2:1 ratio of SB-HD to DDP showed synergistic effects in reducing ovarian cancer cell viability, promoting apoptosis, and inhibiting cell migration; in animal models, this combination significantly suppressed tumor growth while minimizing DDP's toxic side effects.
- The mechanism behind this synergistic effect involves promoting oxidative stress, altering energy production, and modulating specific
Objective: Despite the combination of Scutellaria barbata D. Don and Scleromitrion diffusum (Willd.) R.
View Article and Find Full Text PDF[Using two-dimensional gel electrophoresis to analyze the regeneration microenvironment of facial nerve and its response to acupuncture].
Sichuan Da Xue Xue Bao Yi Xue Ban
April 2003
Objective: To investigate the distribution of proteins in the regeneration microenvironment of facial nerve and its response to acupuncture.
Methods: We created an animal model using rabbit to imitate the regeneration microenvironment of facial nerve and analyzed the proteins in the microenvironment through the two-dimensional gel electrophoresis.
Results: We found that most proteins in the regeneration fluid were under relative molecular mass 80 x 10(3) and in the range of pI 4-7.
[Proteomics analysis and biochemical activity detection on facial nerve regeneration fluid].
Lin Chuang Er Bi Yan Hou Ke Za Zhi
January 2003
Objective: To explore the protein components and the biological neutrional activity upon motor neuron, so that take a general, basic study on the nerve regeneration microenvironment which be important to facial nerve regeneration.
Method: The animal model of rabbit facial regeneration microenvironment is established. Advanced technology of two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) was used to study on the structural proteins in the regeneration fluid, as well as the motor neuron culture was used to test the biological activity in it.