Publications by authors named "Bingqin Huang"
Article Synopsis
- - Studies validate the effectiveness of spectral CT in predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC), highlighting differences between conventional and spectral CT results that require further research.
- - This retrospective study analyzed 105 small HCC cases, categorizing patients into MVI-negative and MVI-positive groups based on pathology, to assess various imaging features and iodine density from spectral CT scans.
- - Results showed significant differences in specific imaging features and iodine densities between MVI-negative and MVI-positive groups, with certain features demonstrating high diagnostic accuracy, ultimately leading to effective predictive models combining imaging features and iodine density.
Article Synopsis
- The study aimed to validate radiomics models for predicting cognitive impairment in patients with cerebral small vessel disease (CSVD), categorizing participants into mild and severe impairment groups based on Montreal Cognitive Assessment (MoCA) scores.
- Researchers used hippocampal radiomic features, applying methods to process data and create diagnostic models, which were then evaluated for accuracy, sensitivity, and specificity.
- Results showed varying effectiveness of the model in distinguishing between cognitive impairment levels, with better performance in identifying severe impairment compared to mild impairment, highlighting inconsistencies in diagnostic efficacy.
Aims: Cerebral small vessel disease (CSVD) is a complex condition characterized by a combination of microcirculation disorders and neurodegenerative processes, CSVD is associated with structural abnormalities in multiple brain regions. However, the progressive pattern of structural changes remains unknown.
Methods: In order to detail the progressive structural changes in CSVD patients according to the degree of cognitive impairment, we recruited 121 CSVD patients and 104 healthy controls (HCs).
Article Synopsis
- This study investigates changes in brain activity and connectivity in patients with mild and major vascular cognitive impairment (VCI) due to cerebral small vessel disease (CSVD).
- A total of 114 patients were analyzed, comparing their brain function to that of healthy subjects through neuropsychological tests and MRI scans, assessing the relationship between brain activity and cognitive function.
- Results showed that VCI patients had abnormal brain activity in specific regions and reduced connectivity, with these disruptions worsening alongside cognitive decline, particularly noting the role of increased activity in certain brain areas as a mediator of cognitive impairment.
Mental health problems in nurses are prevalent and impairing. To date, no literature has comprehensively synthesised cohort evidence on mental health among nurses. This scoping review aimed to synthesise the existing literature on the risk factors and consequences of mental health problems in nurses.
View Article and Find Full Text PDFBackground: Neurodegeneration has been suggested to be associated with cerebral small vessel disease (CSVD). The association between different CSVD imaging markers and the extent of neurodegeneration could be indirectly confirmed by examining the relationship between CSVD imaging markers and the hippocampal amide proton transfer (APT) values. The associations between hippocampal APT values with CSVD imaging markers and CSVD total load need to be further validated.
View Article and Find Full Text PDFBackground: Prostate cancer invades the capsule is a key factor in selecting appropriate treatment methods. Accurate preoperative prediction of extraprostatic extension (EPE) can help achieve precise selection of treatment plans.
Purpose: The aim of this study is to verify the diagnostic efficacy of tumor size, length of capsular contact (LCC), apparent diffusion coefficient (ADC), and Amide proton transfer (APT) value in predicting EPE.
Backgroud: Emerging evidence suggests an overlap in the underlying pathways contributing to both cerebral small vessel disease (CSVD) and the neurodegenerative disease. Studies investigating the progression of CSVD should incorporate markers that reflect neurodegenerative lesions.
Objective: We aim to investigate whether Amide proton transfer (APT) can serve as a potential marker for reflecting vascular cognitive impairment (VCI).
Three phenolic acids including p-hydroxybenzoic acid (PHBA), 3,4-dihydroxybenzoic acid, (DHBA), and gallic acid (GA) were grafted onto native pectin (Na-Pe) through enzymatic method. Ultraviolet-visible spectrometry, Fourier transform infrared spectroscopy, and H NMR analyses were used to explore the reaction mechanism. Results indicated that the p-hydroxyl of the phenolic acids reacted with the methoxycarbonyl of pectin through transesterification, and a covalent connection was formed.
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