The effect of 'detailing' on physicians' prescribing behavior for postsurgical narcotic analgesia.

Physicians have been frequently reported to prescribe inadequately pain medication in the hospitalized patient. A number of methods and techniques have been attempted to alter this phenomenon including audit, standard setting, drug utilization evaluation and sanctioning. The purpose of the following study was to demonstrate the behavioral efficacy of the technique of detailing.

Maternal effects in human cleft lip and palate.

To look for a persistent maternal effect of CL(P) and CP, 8,000 pedigrees were screened for half sibships, and data were pooled from 16 investigators. After excluding known genetic or cytogenetic diagnoses from the probands with facial clefts, a recurrence risk of .011 was obtained for CL(P) based upon 342 maternal half sibs.

Asymmetric septal hypertrophy in a large amish kindred.

We report a large Amish kindred in which asymmetric septal hypertrophy (ASH) appeared to segregate as an autosomal dominant gene. This kindred was ascertained through a 3-month-old infant and her father. The striking differences between father and daughter regarding clinical presentation and course exemplify the variable expressivity of this condition.

Polydactyly in the American Indian.

Polydactyly has an incidence in the American Indian twice that of Caucasians. A minimum estimate of this incidence is 2.40 per 1,000 live births.