The association between post-lunch napping duration and social participation among the Chinese older adults: a cross-sectional study.

Background: Social participation (SP) affects the physical and mental health of older adults. Post-lunch napping is a prevalent lifestyle practice observed among older adults, and it may have an impact on their SP. However, research that explores the association between these factors is limited, and we thus aimed to examine this association.

Bafilomycin A1 inhibits SARS-CoV-2 infection in a human lung xenograft mouse model.

Coronavirus disease 2019 is a global pandemic caused by SARS-CoV-2. The emergence of its variant strains has posed a considerable challenge to clinical treatment. Therefore, drugs capable of inhibiting SARS-CoV-2 infection, regardless of virus variations, are in urgently need.

Multivalent SnO quantum dot-decorated TiC MXene for highly sensitive electrochemical detection of Sudan I in food.

Quantum dots functionalization has been proven to be a simple modification strategy for improving the electroanalytical performance of two-dimensional electrode materials by increasing the specific surface area and active reaction sites. Herein, a new electrochemical sensing platform was fabricated by SnO quantum dot-functionalized TiC MXene (TiC-SnOQDs) for the highly sensitive detection of Sudan I in food. TiC-SnOQDs were prepared synthesis, which can control the nucleation and growth of SnOQDs, resulting in the well-dispersed SnOQDs with 2-3 nm size on the intersheet surface of MXene.

Host Cells Actively Resist Porcine Reproductive and Respiratory Syndrome Virus Infection via the IRF8-MicroRNA-10a-SRP14 Regulatory Pathway.

MicroRNAs (miRNAs) play an important role in the virus-host interaction. Our previous work has indicated that the expression level of miR-10a increased in porcine alveolar macrophages (PAMs) during porcine reproductive and respiratory syndrome virus (PRRSV) infection and further inhibited viral replication through downregulates the expression of host molecule signal-recognition particle 14 (SRP14) protein. However, the molecular mechanism of miR-10a increased after PRRSV infection remains unknown.