ppb-Level SO Photoacoustic Sensor for SF Decomposition Analysis Utilizing a High-Power UV Laser with a Power Normalization Method.

A highly sensitive sulfur dioxide (SO) photoacoustic gas sensor was developed for the sulfur hexafluoride (SF) decomposition detection in electric power systems by using a novel 266 nm low-cost high-power solid-state pulse laser and a high -factor differential photoacoustic cell. The ultraviolet (UV) pulse laser is based on a passive -switching technology with a high output power of 28 mW. The photoacoustic signal was normalized to the laser power to solve the fluctuation of the photoacoustic signal due to the power instability of the UV laser.

C118P Suppresses Gastric Cancer Growth via Promoting Autophagy-Lysosomal Degradation of RAB1A.

: Gastric cancer (GC) is the leading cause of cancer-related deaths worldwide. C118P, a microtubule inhibitor with anti-angiogenic and vascular-disrupting activities, was proven to be cytotoxic to various cancer cell lines. This study aimed to explore the anti-tumor effect of C118P against gastric cancer and identify its potential target.

Drug Delivery Across the Blood-Brain Barrier: A New Strategy for the Treatment of Neurological Diseases.

The blood-brain barrier (BBB) serves as a highly selective barrier between the blood and the central nervous system (CNS), and its main function is to protect the brain from foreign substances. This physiological property plays a crucial role in maintaining CNS homeostasis, but at the same time greatly limits the delivery of drug molecules to the CNS, thus posing a major challenge for the treatment of neurological diseases. Given that the high incidence and low cure rate of neurological diseases have become a global public health problem, the development of effective BBB penetration technologies is important for enhancing the efficiency of CNS drug delivery, reducing systemic toxicity, and improving the therapeutic outcomes of neurological diseases.

The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review.

Psoriasis is a chronic inflammatory polygenic disease with significant impacts on skin and joints, leading to substantial treatment challenges and healthcare costs. The quest for novel therapeutic avenues has recently highlighted extracellular vesicles (EVs) due to their potential as biomarkers and therapeutic agents in autoimmune diseases, including psoriasis. EVs are nano-sized, lipid membrane-bound particles secreted by cells that have emerged as promising tools for targeted drug delivery, owing to their unique structure.

The Intra-Articular Delivery of a Low-Dose Adeno-Associated Virus-IL-1 Receptor Antagonist Vector Alleviates the Progress of Arthritis in an Osteoarthritis Rat Model.

Interleukin-1 (IL-1) is a pivotal mediator in the pathological progression of osteoarthritis (OA), playing a central role in disease progression. However, the rapid clearance of IL-1 receptor antagonist (IL-1Ra) from the joints may hinder the efficacy of intra-articular IL-1Ra injections in reducing OA-associated pain or cartilage degradation. Sustaining sufficient levels of IL-1Ra within the joints via adeno-associated virus (AAV)-mediated gene therapy presents a promising therapeutic strategy for OA.

A Novel Polytetrahydrofuran-Based Shape Memory Polyurethane Enhanced by Polyglycolide-Block-Polytetrahydrofuran-Block-Polyglycolide Copolymer.

A series of polyurethanes (PU-GT) were prepared using polyglycolide-block-polytetrahydrofuran-block-polyglycolide (PGA-PTHF-PGA), polytetrahydrofuran homopolymer (PTHF), glycerol, and hexamethylene diisocyanate (HDI) by a one-pot synthesis method. The non-isothermal crystallization and subsequent heating curves showed that the PTHF component in these polyurethanes could crystallize in a temperature range of -11.5~2.

Investigation into the Reinforcement Modification of Natural Plant Fibers and the Sustainable Development of Thermoplastic Natural Plant Fiber Composites.

Natural plant fibers (NPFs) have emerged as a sustainable alternative in the manufacture of composites due to their renewability and low environmental impact. This has led to a significant increase in the use of natural plant fiber-reinforced polymers (NPFRPs) in a variety of industries. The diversity of NPF types brings a wide range of properties and functionalities to NPFRPs, which in turn highlights the urgent need to improve the properties of fiber materials in order to enhance their performance and suitability.

Switchable Solvent for Separation and Extraction of Lignin from Lignocellulose Biomass: An Investigation of Chemical Structure and Molecular Weight.

Lignin, the most abundant natural aromatic polymer, holds considerable promise for applications in various industries. The primary obstacle to the valorization of lignin into useful materials is its low molecular weight and diminished chemical reactivity, attributable to its intricate structure. This study aimed to treat lignocellulosic biomass using a switchable solvent (DBU-HexOH/HO) derived from the non-nucleophilic superbase 1,8-diazabicyclo [5.

The Network Construction of a New Byproduct-Free XLPE-Based Insulation Using a Click Chemistry-Type Reaction and a Theoretical Study of the Reaction Mechanism.

Cross-linked polyethylene (XLPE) is applied in most advanced high-voltage direct-current (HVDC) power cable insulations, which are produced via dicumyl peroxide (DCP) technology. The electrical conductivity of insulation material can be increased by cross-linking byproducts from the DCP process. Hence, currently much attention is being paid to a new process to produce cross-linking byproduct-free XLPE.

Study on Mechanical Properties and Carbon Emission Analysis of Polypropylene Fiber-Reinforced Brick Aggregate Concrete.

Given the current construction waste accumulation problem, to utilize the resource of red brick solid waste, construction waste red brick was used as a concrete coarse aggregate combined with polypropylene fiber to prepare PPF (polypropylene fiber)-reinforced recycled brick aggregate concrete. Through a cube compression test, axial compression test, and four-point bending test of 15 groups of specimens, the influences of the aggregate replacement rate of recycled brick and the PPF volume on the mechanical properties of recycled brick aggregate concrete reinforced by PPF were studied, and a strength parameter calculation formula was constructed and modified based on the above. Finally, combined with a life cycle assessment (LCA), the carbon emissions of raw materials were analyzed and evaluated.

Recent Advances in Polyurethane for Artificial Vascular Application.

Artificial blood vessels made from polyurethane (PU) have been researched for many years but are not yet in clinical use. The main reason was that the PU materials are prone to degradation after contact with blood and will also cause inflammation after long-term implantation. At present, PU has made progress in biostability and biocompatibility, respectively.

Study on the Characterization of Physical, Mechanical, and Creep Properties of Masson Pine and Chinese Fir Wood Flour-Reinforced High-Density Polyethylene Composites.

Improving the physical, mechanical, and creep properties of wood fiber-reinforced polymer composites is crucial for broadening their application prospect. In this research, seven types of high-density polyethylene (HDPE) composites reinforced with different mass ratios of Masson pine ( Lamb.) and Chinese fir [ (Lamb.

Cumulative Strain and Improvement Mechanisms of Soil Reinforced by Xanthan Gum Biopolymer Under Traffic Loading.

As is widely accepted, cumulative strain and improvement mechanisms of stabilized soil are critical factors for the long-term reliable operation of expressways and high-speed railways. Based on relevant research findings, xanthan gum biopolymer is regarded as a green and environmentally friendly curing agent in comparison to traditional stabilizers, such as cement, lime, and fly ash. However, little attention has been devoted to the cumulative strain and improvement mechanisms of soil reinforced by xanthan gum biopolymer under traffic loading.

Modeling of Accumulator in Roll-to-Roll Coating Equipment and Tension Control with Nonlinear PID.

This paper addresses the issue of the high-precision control of substrate tension in an accumulator during the roll-to-roll coating process. First, a coupling model for tension errors in the substrate within the accumulator is established, along with dynamic models for the input-output rollers, carriage, and the thrust model of the ball screw. Based on these models, a simulation model is built in MATLAB/Simulink to analyze the main causes of substrate tension errors in the accumulator under uncontrolled conditions.

Preparation and Characterization of a Novel Self-Healing Transparent Polyimide Film Based on Dynamic Disulfide Bonds.

Self-healing optically transparent polyimides have potential applications in optoelectronic device fabrication. In this study, for the first time, we successfully prepared a novel self-healing polyimide film containing reversible disulfide bonds through chemical imidization by introducing cystamine as a self-healing functional monomer into the molecular structure of conventional polyimides. The incorporation of cystamine enabled the films to maintain high transmittance (>87%) and tensile strength (>99 MPa).

Comparative Physiological and Transcriptomics Profiling Provides Integrated Insight into Melatonin Mediated Salt and Copper Stress Tolerance in L.

L., (pitaya) is an important tropical fruit crop, and faces significant challenges from soil salinity and heavy metal toxicity. This study explores the role of melatonin (M) in enhancing stress tolerance in pitaya against salinity (S) and copper (Cu) toxicity, both individually and in combination (SCu).

Effects of Exogenous Spermidine on Seed Germination and Physiological Metabolism of Rice Under NaCl Stress.

Salt stress is one of the principal abiotic stresses limiting agricultural production and seriously inhibiting seed germination rates. This study selected the salt-tolerant rice variety HD961 and the salt-sensitive rice variety 9311 as experimental materials to investigate the physiological and metabolic effects of exogenous Spd seed priming on rice seeds and seedlings under NaCl stress. The experiment involved treating rice seeds with 0.

The Ameliorative Effect of Coumarin on Copper Toxicity in : Insights from Growth, Nutrient Uptake, Oxidative Damage, and Photosynthetic Performance.

Excessive copper (Cu) has become a common physiological disorder restricting the sustainable production of citrus. Coumarin (COU) is a hydroxycinnamic acid that can protect plants from heavy metal toxicity. No data to date are available on the ameliorative effect of COU on plant Cu toxicity.

Defense-Related Enzyme Activities and Metabolomic Analysis Reveal Differentially Accumulated Metabolites and Response Pathways for Sheath Blight Resistance in Rice.

Rice sheath blight (RSB), caused by the pathogenic fungus , poses a significant threat to global food security. The defense mechanisms employed by rice against RSB are not well understood. In our study, we analyzed the interactions between rice and by comparing the phenotypic changes, ROS content, and metabolite variations in both tolerant and susceptible rice varieties during the early stages of fungal infection.

Somatic Embryogenesis from the Leaf-Derived Calli of In Vitro Shoot-Regenerated Plantlets of 'Carola'.

Roses are one of the most important flowers applied to landscape, cut flowers, fragrance and food industries widely. As an effective method for plant reproduction, the regeneration via somatic embryos is the most promising method for breed improvement and genetic transformation of woody plants. However, lower somatic embryogenesis (SE) induction rates and genotypic constraints impede progress in genetic transformation in rose.

Insights into the Genomic Background of Nine Common Chinese Medicinal Plants by Flow Cytometry and Genome Survey.

Medicinal plants have long played a crucial role in healthcare systems, but limited genomic information on these species has impeded the integration of modern biological technologies into medicinal plant research. In this study, we selected nine common medicinal plants, each belonging to a different plant family, including (Chloranthaceae), (Vitaceae), (Fabaceae), (Cucurbitaceae), (Polygonaceae), (Caryophyllaceae), (Rubiaceae), (Lamiaceae), and (Asteraceae), to estimate their genome sizes and conduct preliminary genomic surveys. The estimated genome sizes by flow cytometry were 3.

Isolation, Characterization, and Proteomic Analysis of Crude and Purified Extracellular Vesicles Extracted from f. sp. .

Extracellular vesicles (EVs) produced by f. sp. () play vital roles in plant-pathogen interactions; however, the isolation of purified TR4-EVs and their pathogenicity and proteomic profiles are not well studied.

Colchicine-Induced Tetraploidy in Protocorms of Lodd. ex Lindl. and Paxton. and Its Identification.

(Orchidaceae) boasts high ornamental value due to its pleasant aroma, foxtail spike, and elegant floral morphology. Inducing to become tetraploid enhances horticultural traits and facilitates fertile intergeneric hybrids through crosses with other market-available tetraploid species. The experimental design involved the application of colchicine at varying concentrations-0.

Impact of Different Land-Use Types on Soil Microbial Carbon Metabolism Function in Arid Region of Alpine Grassland.

There are discrepancies that exist in the effects of different land uses on soil organic carbon (SOC) and soil microbial carbon metabolism functions. However, the impact of land-use type changes on soil microbial carbon metabolism in alpine grassland arid areas is not well understood, hindering our understanding of the carbon cycling processes in these ecosystems. Therefore, we chose three types of land use (continuous reclamation of grassland (RG), abandoned grassland (AG), and natural grazing grassland (GG)) to study the microbial carbon metabolism and its driving factors by the Biolog-ECO method.

One-Off Irrigation Combined Subsoiling and Nitrogen Management Enhances Wheat Grain Yield by Optimizing Physiological Characteristics in Leaves in Dryland Regions.

Irrigation practice, tillage method, and nitrogen (N) management are the three most important agronomic measures for wheat ( L.) production, but the combined effects on grain yield and wheat physiological characteristics are still poorly understood. We conducted a three-year split-split field experiment at the junction of the Loess Plateau and Huang-Huai-Hai Plain in China.