Association of meibomian gland morphology with orifice plugging and lid margin thickening in meibomian gland dysfunction patients.

Purpose: We sought to investigate the association of meibomian gland morphology with lid margin abnormalities in patients with meibomian gland dysfunction.

Methods: This retrospective study included 368 eyes of 184 patients. Meibography was used to evaluate meibomian gland (MG) morphological features, such as dropout, distortion, thickened ratio and thinned ratio.

Gp130 Promotes Inflammation via the STAT3/JAK2 Pathway in Allergic Conjunctivitis.

Purpose: Allergic conjunctivitis (AC) is a common allergic condition worldwide that requires accurate screening and early diagnosis. We found that gp130 is essential for AC, as gp130 levels are elevated in AC. Therefore, this study aimed to elucidate the functions and the possible underlying mechanisms of gp130 in AC.

Total IgE in tears accurately reflects the severity and predicts the prognosis of seasonal allergic conjunctivitis.

Background: Although immunoglobulin E (IgE) increases significantly in tears and serum during seasonal allergic conjunctivitis (SAC), it is unclear whether tear total IgE can reflect the severity and prognosis of SAC more accurately than serum total IgE. We aimed to investigate the usefulness of measuring the total IgE in tears to evaluate the severity and determine the treatment of SAC.

Methods: This prospective, nonrandomized study involved 55 patients with SAC and 10 age- and sex-matched healthy controls.

Effect of hypothermic perfusion on phacoemulsification in cataract patients complicated with uveitis: a randomised trial.

Background: To evaluate the effectiveness and safety of hypothermic perfusion in the phacoemulsification of cataract caused by uveitis.

Methods: This was a prospective, single-masked, randomised, controlled clinical trial. One hundred and six patients with uveitis-associated cataract underwent phacoemulsification with perfusion fluid temperature at 4 °C (treatment group) or 24 °C (control group).

Rab18 overexpression promotes proliferation and chemoresistance through regulation of mitochondrial function in human gastric cancer.

Background: Dysregulation of Rab18 has been implicated in human cancers. However, its clinical significance and biological function in gastric cancer have not been investigated.

Methods: We examined Rab18 expression in gastric cancer tissues using immunohistochemistry.