Publications by authors named "BingKun Chen"

Article Synopsis
  • Traditional snapshot techniques in long-wave infrared imaging lose significant optical energy due to the use of broadband filters, prompting the need for a more efficient solution.
  • The authors propose replacing these filters with specially designed diffractive elements optimized through a gradient descent algorithm, which improves optical energy efficiency by steering wavelengths to designated pixels.
  • A MST neural network is then employed to reconstruct spectral information, allowing for high-quality imaging and adaptability to changes in the image plane, as demonstrated through emulation experiments.
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Feature detection and description are crucial for image matching, as better performance at this stage leads to more accurate matching results, which is essential for subsequent vision-based tasks. However, images captured by different optical systems may suffer from various optical aberrations, especially in off-axis field and out-of-depth-of-field regions, making it challenging for models to extract consistent feature locations and descriptors. In this paper, we propose what we believe to be a novel method for training feature detection and description networks by incorporating optical system aberrations modeled by point spread function(PSF).

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Glass-plastic hybrid lens systems are increasingly critical in various optical applications due to their unique advantages and growing demands. Due to limitations in manufacturing processes and costs, the yield rate of glass-plastic hybrid lens systems in mass production struggles to match that of mature all-plastic ones. In this work, we propose a pioneering joint hardware-software optimization framework designed for correcting optical degradation in manufacturing-perturbed glass-plastic hybrid lens systems.

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Background: Early detection and treatment of colorectal cancer (CRC) is crucial for improving patient survival rates. This study aims to identify signature molecules associated with CRC, which can serve as valuable indicators for clinical hematological screening.

Method: We have systematically searched the Human Protein Atlas database and the relevant literature for blood protein-coding genes.

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Recycling and reuse of agricultural plastics is an urgent worldwide issue. In this work, it is shown that low-density polyethylene (PE) typically used in mulch films can be converted into high-capacity P and N adsorbents through a two-step method that uses hydrothermal pretreatment (180 °C, 24 h) followed by pyrolysis at 500 °C with Ca(OH) additive. CaPE@HC500 materials prepared with the proposed two-step method were found to have high adsorption capacities for phosphate (263.

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Due to the intrinsic polarized emission property, polarized emissive materials with anisotropic nanostructures are expected to be potential substitutes for polarizers. Herein, by the template-assisted strategy, well-aligned lead-free metal halide CsCuI nanowire (NW) arrays are fabricated by evaporating the precursor ink in the anodic aluminum oxide (AAO) for polarized emission. The CsCuI/AAO composite film emits highly polarized light with a degree of polarization (DOP) of 0.

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The roles of oxygen vacancies to enhance the electrochemical performance were not clearly explained in comprehensive research. Herein, the vertically oriented NiCoS/MnO core-shell nanocomposites are in situ grown on the nickel foam (NF) surface and activated by oxygen vacancy engineering via a chemical reduction method. The scanning electron microscope (SEM) and transmission electron microscope (TEM) results show the shell-MnO is well coated on the core-NiCoS.

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The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising approach to treating a spinal cord injury (SCI) is the use of biomaterials. We have developed a novel hydrogel scaffold fabricated from oligo(poly(ethylene glycol) fumarate) (OPF) as a 0.

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Background: Sialic acid-binding immunoglobulin-like lectin-15 (Siglec-15) was reported to be a novel immune checkpoint molecule comparable to programmed cell death 1 ligand 1 (PD-L1). However, its expression profile and immunosuppressive mechanisms in the glioma tumor microenvironment have not yet been fully explored.

Objectives: To identify the expression profile and potential function of Siglec-15 in glioma tumor microenvironment.

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Article Synopsis
  • - The study investigates how newly regenerated axons using scaffolds and epidural electrical stimulation (EES) can improve spinal cord circuitry and motor functions after spinal cord injury (SCI).
  • - Over 7 weeks, treatments combining scaffolds with neurotrophin-producing Schwann cells and EES led to significant motor function recovery compared to using scaffolds or EES alone, even though the number of regenerated axons was similar across groups.
  • - When researchers re-transected the spinal cord at week 6, motor performance still exceeded that of other groups, indicating that the combined therapies promote synaptic reorganization and enhanced motor recovery after SCI.
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Article Synopsis
  • - Oxidative stress contributes to various inflammatory diseases like allergies, heart disease, diabetes, and cancer, making antioxidant therapies important for treatment.
  • - Defective Ag-In-S/ZnS quantum dots (AIS/ZnS QDs) are developed to effectively scavenge oxygen-derived free radicals, showcasing their ability to reduce oxidative stress in macrophages.
  • - AIS/ZnS QDs not only eliminate harmful reactive oxygen species in macrophages but also exhibit anti-inflammatory properties by reducing pro-inflammatory cytokines in inflammation models, suggesting their potential as a treatment for related disorders.
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Single-pixel imaging, with the advantages of a wide spectrum, beyond-visual-field imaging, and robustness to light scattering, has attracted increasing attention in recent years. Fourier single-pixel imaging (FSI) can reconstruct sharp images under sub-Nyquist sampling. However, the conventional FSI has difficulty balancing imaging quality and efficiency.

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Positively charged oligo(poly(ethylene glycol) fumarate) (OPF+) hydrogel scaffolds, implanted into a complete transection spinal cord injury (SCI), facilitate a permissive regenerative environment and provide a platform for controlled observation of repair mechanisms. Axonal regeneration after SCI is critically dependent upon nutrients and oxygen from a newly formed blood supply. Our objective was to investigate fundamental characteristics of revascularization in association with the ingrowth of axons into hydrogel scaffolds, thereby defining spatial relationships between axons and the neovasculature.

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Dual-emitting manganese ion doped LaMAlO (M = Mg, Zn) phosphors were prepared by substituting Zn/Mg with Mn and replacing Al with Mn. The LaMAlO:xMn,yMn phosphors show a narrow green emission band of the Mn ions at 514 nm and a red emission band of the Mn ions at 677 nm. In addition, the thermal stability of luminescence shows that the response of Mn and Mn to the temperature is obviously different in LaMAlO, implying the potential of the prepared phosphors as optical thermometers.

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Study Design: Animal study.

Objectives: Umbilical cord-derived mesenchymal stem cells (UC-MSCs) have recently been shown to hold great therapeutic potential for spinal cord injury (SCI). However, majority of the studies have been done using human cells transplanted into the rat with immunosuppression; this may not represent the outcomes that occur in humans.

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Article Synopsis
  • Neuromodulation technologies show promise in improving motor functions after spinal cord injury (SCI) by enhancing excitability in the spinal networks below the injury site, independent of brain signals.
  • The review assesses how spinal circuits can adapt and reorganize when sensory inputs are present during motor training, leading to potential recovery mechanisms.
  • The implications of these findings suggest that future advancements in neuromodulation and rehabilitation can significantly benefit functional recovery, including the development of neuroprosthetics.
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Article Synopsis
  • CdS nanotubes are created by folding compounds under specific conditions, using a thermal evaporation technique that involves Sn metal nanowires as templates.
  • These nanotubes exhibit significantly higher quality factors (around 400) compared to core-shell Sn/CdS nanowires, particularly in the optical range of 550-800 nm.
  • The high quality factor enables low-threshold lasing and improved mode selection, making these nanotubes promising for applications in lasers, sensors, and optical storage devices.
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Hydrogel scaffolds provide a beneficial microenvironment in transected rat spinal cord. A combinatorial biomaterials-based strategy provided a microenvironment that facilitated regeneration while reducing foreign body reaction to the three-dimensional spinal cord construct. We used poly lactic-co-glycolic acid microspheres to provide sustained release of rapamycin from Schwann cell (SC)-loaded, positively charged oligo-polyethylene glycol fumarate scaffolds.

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Nanoscale heterostructures, which incorporate two or more materials such as core-shell nanocrystals, core-crown nanoplates, or seeded nanorods, allow better control of the optical, electrical and magnetic properties that are inaccessible in single component nanostructure, yet their variety and controlled growth are still challenging. Here, a nail-like Mn-doped CdS/CdBr hetero-nanostructure, which has a hexagonal plate on top of a nanowire, is firstly fabricated by a simple one-step thermal evaporation process. According to the characterization results, its growth mechanism could be obtained, in which the manganese bromide precursor plays a critical role in the formation of such nail morphology.

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Quantum dots with fabulous size-dependent and color-tunable emissions remained as one of the most exciting inventories in nanomaterials for the last 3 decades. Even though a large number of such dot nanocrystals were developed, CdSe still remained as unbeatable and highly trusted lighting nanocrystals. Beyond these, the ternary I-III-VI family of nanocrystals emerged as the most widely accepted greener materials with efficient emissions tunable in visible as well as NIR spectral windows.

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A top-down method is demonstrated for the fabrication of CH NH PbBr and CH NH PbI perovskite nanocrystals, employing a mixture of ligands oleic acid and oleylamine as coordinating solvents. This approach avoids the use of any polar solvents, skips multiple reaction steps by employing a simple ultrasonic treatment of the perovskite precursors, and yields rather monodisperse blue-, green-, and red-emitting methylammonium lead halide nanocrystals with a high photoluminescence quantum yield (up to 72 % for the green-emitting nanocrystals) and remarkably improved stability. After discussing all relevant reaction parameters, the green-emitting CH NH PbBr nanocrystals are employed as a component of down-conversion white-light-emitting devices

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Article Synopsis
  • Metal nanoclusters (NCs) are tiny structures made of few to hundreds of atoms, falling between nanoparticles and molecular compounds, with a focus on copper NCs due to their affordability and abundance.
  • The review covers various wet chemical synthesis methods for copper NCs, highlighting the importance of surface protecting agents that influence the clusters' stability and properties.
  • It also discusses the optical characteristics of copper NCs, including how factors like the metal core and surrounding environment affect their light emission, and explores their potential applications in fields such as biological imaging and light-emitting devices.
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Positively-charged oligo[poly(ethylene glycol)fumarate] (OPF ) is a biodegradable hydrogel used for spinal cord injury repair. We compared scaffolds containing primary Schwann cells (SCs) to scaffolds delivering SCs genetically modified to secrete high concentrations of glial cell-derived neurotrophic factor (GDNF). Multichannel OPF scaffolds loaded with SCs or GDNF-SCs were implanted into transected rat spinal cords for 4 weeks.

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Most of the present-day down-conversion white light-emitting devices (WLEDs) utilize rare-earth elements, which are expensive and facing the problem of shortage in supply. WLEDs based on the combination of orange and blue emitting copper nanoclusters are introduced, which are easy to produce and low in cost. Orange emitting Cu nanoclusters (NCs) are synthesized using glutathione as both the reduction agent and stabilizer, followed by solvent induced aggregation leading to the emission enhancement.

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Article Synopsis
  • Researchers created flexible films using carboxylated polyurethane and aggregated copper nanoclusters, achieving dual emission peaks in blue and orange wavelengths.* -
  • The films exhibit high transparency and maintain over 90% of their light emission after repeated stretching and high-temperature aging, indicating good mechanical stability.* -
  • These films were used to produce white light-emitting devices (LEDs) that achieved desirable color coordinates and a high color rendering index, making them suitable for optoelectronic applications.*
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