[Molluscicidal activity of 25% wettable powder of pyriclobenzuron sulphate against ].

Objective: To evaluate the molluscicidal activity of a novel molluscicide pyriclobenzuron against in the mountain regions of Yunan Province, and test its toxicity to fish, so as to provide scientific evidence for the extensive application of this molluscicide in schistosomiasis-endemic foci of Yunan Province.

Methods: In the laboratory and snail-breeding field of Dali Prefecture, Yunnan Province, the molluscicidal activity of 5% wettable powder of pyriclobenzuron sulphate (25% PBU) against was assessed by using the immersion and spraying method, and the acute toxicity of 25% PBU to carp fries was tested, while 25% wettable powder of niclosamide ethanolamine salt (50% WPNES) served as a control.

Results: The 1-, 2- and 3-day 25% PBU LC50 and LC90 values were 0.

[Molluscicidal effect and mechanism of action of niclosamidate against ].

Objective: To evaluate the molluscicidal effect of niclosamidate against in laboratory and explore its mechanism by determining the enzyme activities of six important enzymes in snail soft tissues.

Methods: snails were treated with niclosamidate at the concentration of 1.25 mg/L for 24 h and the snail soft tissues were separated and prepared for analysis.

[Effect of comprehensive schistosomiasis control measures based on infection source control in mountainous areas of Yunnan Province].

Objective: To evaluate the effect of comprehensive schistosomiasis control measures based on infection source control in plateau mountain areas of Yunnan Province.

Methods: From 2006 to 2004, four administrative villages were selected as test areas from plateau canyon and plateau basin endemic areas in Jindun Town, Heqing County, two villages each type, and the comprehensive control measures were implemented, including the examination and treatment of schistosomiasis, Oncomelania hupensis snail survey and control, health education, improving drinking water and lavatories, banning grazing, constructing sanitary pen of livestock, replacing cattle with machine, etc. The schistosome infection state and snail status in 2006 were treated as the baseline information, and the effect of the comprehensive measures were evaluated.

[Molluscicidal effect of WPN and MNSC on Lymnaea].

Objective: To evaluate the molluscicidal effect of wettable powder of 50% niclosamide ethanolamide salt (WPN) and suspension concentrate of 26% metaldehyde and niclosamide (MNSC) on Lymnaea.

Methods: WPN and MNSC were prepared as a series of solutions containing the active ingredient concentrations of 0.06, 0.

[Effect of comprehensive control and management of schistosomiasis at plateaus regions in Yunnan Province].

Objective: To evaluate the effect of comprehensive control and management of schistosomiasis at plateaus regions in Yunnan Province.

Methods: Xiaolian and Kangfu villages at plateaus regions where schistosomiasis was endemic were selected as study areas from 2006 to 2011, the schistosomiasis comprehensive control measures were conducted, and these measures included the health education, chemotherapy, stool and water management, grazing forbidden, Oncomelania snail control, etc. combined with the infrastructure of farmland water conservancy, agricultural comprehensive development, adjustment of industry structure, returning farmland to forest, ditch hardening, and aquaculture.