The application of deep eutectic solvent on the extraction and in vitro antioxidant activity of rutin from bud.

The extraction conditions and antioxidant activities of rutin from bud by deep eutectic solvents were investigated. Box-Behnken design was used to optimize the extraction conditions and the scavenging activities of DPPH, O and ·OH of purified rutin were evaluated. The highest yield of 279.