Macular thickness as a predictor of loss of visual sensitivity in ethambutol-induced optic neuropathy.

Ethambutol is a common cause of drug-related optic neuropathy. Prediction of the onset of ethambutol-induced optic neuropathy and consequent drug withdrawal may be an effective method to stop visual loss. Previous studies have shown that structural injury to the optic nerve occurred earlier than the damage to visual function.

[The interactions of stromal-epithelial in a model of co-culture in the rabbit cornea].

Objective: The purpose of the study is to produce a reconstructed cornea including epithelia and stroma by tissue engineering. The reconstructed tissue may provide a physiologic model for the investigations of interaction between corneal epithelial cells and keratocytes.

Methods: Epithelial cells and keratocytes were isolated from rabbit corneas and cultured on plastic substrates in vitro.

[Experimental retinal vein occlusion induced by photodynamic approach].

Objective: To develop a new photochemical method of experimental retinal vein occlusion and investigate the morphologic and histologic changes in the retina.

Methods: After intravenous injection of rose Bengal, the vessels next to the disc of miniature pigs in the experiment group (n = 15) were exposed to an endo-illuminator for 15 minutes. As a control group, the vessels next to the disc of each pig were exposed to the endo-illuminator without rose Bengal injection.