Publications by authors named "Bing-Cheng Lin"

Secondary copper smelting is an important source of heavy metal emission. Flue gas samples were collected from different stages in secondary copper smelters to study the emission characteristics and control of particulate matters (PM) and heavy metals such as Cd, Cr, As, Pb, Sn, and Sb. The mass concentrations of heavy metals in flue gas and fly ash were determined using inductively coupled plasma-mass spectrometry.

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In this study, high-performance InGaN-based green light-emitting diodes (LEDs) with a quaternary InAlGaN/GaN superlattice electron blocking layer (QSL-EBL) have been demonstrated. The band structural simulation was employed to investigate the electrostatic field and carriers distribution, show that the efficiency and droop behavior can be intensively improved by using a QSL-EBL in LEDs. The QSL-EBL structure can reduce the polarization-related electrostatic fields in the multiple quantum wells (MQWs), leading to a smoother band diagram and a more uniform carriers distribution among the quantum wells under forward bias.

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For the purpose of light extraction and efficiency enhancement, the nitride-based ultraviolet vertical-injection light-emitting diodes (UV-VLEDs) with non-insulation current blocking layer (n-CBL) and optimized textured surface were fabricated. The optical and electrical characteristics were investigated in this n-CBL UV-VLED. Furthermore, the efficiency of optimized structure was improved by 5 ~ 6 times compared to our reference.

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The flip chip ultraviolet light-emitting diodes (FC UV-LEDs) with a wavelength of 365 nm are developed with the ex situ reactive plasma deposited (RPD) AlN nucleation layer on patterned sapphire substrate (PSS) by an atmospheric pressure metal-organic chemical vapor deposition (AP MOCVD). The ex situ RPD AlN nucleation layer can significantly reduce dislocation density and thus improve the crystal quality of the GaN epitaxial layers. Utilizing high-resolution X-ray diffraction, the full width at half maximum of the rocking curve shows that the crystalline quality of the epitaxial layer with the (RPD) AlN nucleation layer is better than that with the low-temperature GaN (LT-GaN) nucleation layer.

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This paper demonstrates the embellishment of existing microfluidic devices with integrated three dimensional (3D) micronanostructures via femtosecond laser micronanofabrication, which, for the first time, proves two-photon photopolymerization (TPP) to be a powerful technology for chip functionalization. As representative examples, microsieves with various pore shape and adjustable pore size were successfully fabricated inside a conventional glass-based microfluidic channel prepared by wet etching for microparticle separation. Moreover, a fish scale like microfilter was also fabricated and appointed as a one-way valve, which showed excellent performance as we expected.

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Microchip-based systems have many desirable characteristics and can be used in much cellular biochemical analysis. Glucose-regulated protein 78 (GRP78), an endoplasmic reticulum chaperone, has a critical role in chemotherapy resistance of some cancers. This work aimed at analyzing the correlation between the expression of GRP78 and an anticancer drug, topoisomerase II inhibitor-VP-16, in human lung cancer cell line NCI-H460 using this microchip-based system.

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Inexpensive and permanently modified poly(methyl methacrylate)(PMMA) microchips were fabricated by an injection-molding process. A novel sealing method for plastic microchips at room temperature was introduced. Run-to-run and chip-to-chip reproducibility was good, with relative standard deviation values between 1-3% for the run-to-run and less than 2.

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Article Synopsis
  • * A study analyzed 153 specimens using a modified PCR method and found abnormal methylation of p16 in various patient samples, including those with lung and abdominal tumors.
  • * Results indicated that a microchip electrophoresis method could enhance detection accuracy by over 26.6% compared to traditional gel electrophoresis, showing promise for early cancer diagnosis.
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Article Synopsis
  • UV labeling detection usually focuses on labeled carbohydrates, but this study introduces a new method to directly detect underivatized saccharides interacting with lectins, specifically glucose and its derivatives.
  • A capillary zone electrophoretic method, using a silica capillary and specific buffer conditions, successfully separates underivatized sugars like glucose and glucosamine within 11 minutes under applied voltage.
  • This method features on-column UV monitoring for detecting and quantifying these sugars at low concentrations, highlighting its simplicity, speed, and reproducibility for analyzing saccharide and lectin interactions.
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Domoic acid, a main component of amnesic shellfish toxin (one of the four sorts of marine red tide bio-toxins) was determined by capillary electrophoresis with UV detection. The shellfish samples were prepared by solvent extraction, cleaned-up with a strong anion-exchange cartridge (SAX: Part No. 1210-2044, Lot No.

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