Two new meroterpenoids from the bark of and their antioxidant activity.

Two new ( and ) meroterpenoids were isolated from the bark of . Their structures were determined by spectroscopic analyses and chemical methods. Antioxidant activities of and were evaluated by the ORAC and DPPH radical scavenging assays, and the results revealed that compound displayed oxygen radical absorbance capacity.

Abnormal methylation characteristics predict chemoresistance and poor prognosis in advanced high-grade serous ovarian cancer.

Background: Primary or acquired chemoresistance is a key link in the high mortality rate of ovarian cancer. There is no reliable method to predict chemoresistance in ovarian cancer. We hypothesized that specific methylation characteristics could distinguish chemoresistant and chemosensitive ovarian cancer patients.