Comparison of clinical effects between sacrospinous ligament fixation and extraperitoneal high uterosacral ligament suspension for patients: A retrospective cohort clinical trials.

Aim: The aim of the study is to compare the effect of extraperitoneal high uterosacral ligament suspension (EHUS) and sacrospinous ligament fixation on lower urinary tract symptoms (LUTS) and anatomical reduction in patients with pelvic organ prolapse (POP).

Methods: This retrospective cohort study concluded 91 patients with POP who underwent EHUS or sacrospinous ligament fixation (SSLF) for apical repair. The primary outcome was the effect of the two operations on anatomical reduction.

sp. nov. and sp. nov., isolated from waste landfill.

Two Gram-stain-positive, oxidase-negative, non-motile and rod-shaped strains (ASV49 and ASV81) were isolated from a waste landfill in Shanghai, China. Phylogenetic analysis based on 16S rRNA gene sequences indicated that the two strains are associated with members of the genus . Strains ASV49 and ASV81 were most closely related to JCM 31396 and CCTCC AA 2018025 with 98.

N-doped biochar-Fe/Mn as a superior peroxymonosulfate activator for enhanced bisphenol a degradation.

Emerging contaminants (ECs) are characterized by their widespread environmental distribution and low concentrations, posing significant challenges for their effective removal from source wastewater. To better deal with the problems associated with ECs, we developed a robust Fe-Mn bimetallic catalyst supported on N-doped biochar (FM@NBC-8) for peroxymonosulfate (PMS)-mediated advanced oxidation system, in which bisphenol A (BPA) was investigated as a typical EC. Particularly, complete degradation of BPA in the FM@NBC-8/PMS system was achieved within 5 min, accompanying with a high TOC removal.

Analysis of Cardiovascular and Cerebrovascular Prognosis and Risk Factors in Patients with Primary Membranous Nephropathy.

Background: This study investigated risk factors and possible mechanisms of arterial and venous thromboembolic events in patients with pMN.

Methods: Patients with pMN confirmed by renal biopsy from June 1, 2010 to March 3, 2023 were included, and the study outcome was set as a composite endpoint of acute coronary syndrome, heart failure, cerebral infarction, arrhythmia, pulmonary embolism, deep venous thrombosis and all-cause mortality.

Results: A total of 433 pMN patients with complete data were included, with a median follow-up time of 73 (45.

Effect of alkaline-thermal pretreatment on biodegradable plastics degradation and dissemination of antibiotic resistance genes in co-compost system.

Biodegradable plastics (BDPs) are an eco-friendly alternative to traditional plastics in organic waste, but their microbial degradation and impact on antibiotic resistance genes (ARGs) transmission during co-composting remain poorly understood. This study examines how alkaline-thermal pretreatment enhances BDPs degradation and influences the fate of ARGs and mobile genetic elements (MGEs) in co-composting. Pretreatment with 0.

Assessment of plantar pressure dynamics in firefighters carrying self-contained breathing apparatus: a computational approach to gait stability analysis.

Firefighters carrying self-contained breathing apparatus (SCBA) during training or firefighting may reduce gait stability and increase the risk of injury. Twelve firefighters participated in treadmill gait experiments while carrying SCBA. Multiscale entropy (MSE) and fused pressure region amplitude ratios were used to assess gait stability and pressure distribution.

Gut microbiota-derived trimethylamine N-oxide involved in methamphetamine-induced depression-like behaviors of male mice.

Methamphetamine (METH)-provoked psychiatric symptoms are a major health concern, with depression being a prevalent symptom among METH abusers. Recently, gut microbiota-derived metabolites have been involved in various psychosis pathogenesis, but their roles in METH-induced depression remain unclear. This study investigates the implication of gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) in METH-induced depressive-like behaviors (DLBs).

A Strategy of Enhancing Polarization to Achieve Excellent Energy Storage Performance in Simple BiKTiO-Based Relaxors.

Dielectric energy storage capacitors are indispensable components in advanced electronic and electrical systems. Excellent performance requires the dielectric materials possessing low residual polarization (P), high breakdown strength (E), and large maximum polarization (P). The first two parameters can be typically achieved through chemical regulation, while the P is closely related to the matrix.

Household waste-specific ambient air shows greater inhalable antimicrobial resistance risks in densely populated communities.

Household waste is a hotspot of antibiotic resistance, which can be readily emitted to the ambient airborne inhalable particulate matters (PM) during the day-long storage in communities. Nevertheless, whether these waste-specific inhalable antibiotic resistance genes (ARGs) are associated with pathogenic bacteria or pose hazards to local residents have yet to be explored. By high-throughput metagenomic sequencing and culture-based antibiotic resistance validation, we analyzed 108 airborne PM and nearby environmental samples collected across different types of residential communities in Shanghai, the most populous city in China.

Ligand Reorganization for End-Point Binding Free Energy Calculations: Identifying Preferred Poses of Fentanyls in the μ Opioid Receptor.

We have developed a method that uses energy landscapes of unbound and bound ligands to compute reorganization free energies for end-point binding free-energy calculations. The method is applied to our previous simulations of fentanyl derivatives bound to the μ opioid receptor in different orientations. Whereas the mean interaction energy provides an ambiguous ranking of binding poses, interaction entropy and ligand reorganization strongly penalize geometric decoys such that native poses observed in CryoEM structures are best ranked.

Polo-like kinase 2 ameliorates lipopolysaccharide-induced cardiac injury by blocking cardiomyocyte ferroptosis.

Background: Polo-like kinase 2 (PLK2) is associated with cardiac fibrosis in patients with atrial fibrillation. However, the role of PLK2 in sepsis-induced cardiac injury has not been fully elucidated. We hypothesize that PLK2 may participate in the progression of sepsis-induced cardiac injury.

Correction: Yu et al. The Role of circTmeff-1 in Morphine Addiction Memory of Mice. 2023, , 1985.

In the original publication [...

Boosting High Electric Breakdown Strength for Excellent Energy Storage Performance in BiNaTiO-Based Lead-Free Ceramics via a High Entropy Strategy.

High-performance dielectric capacitors featuring large recoverable energy storage density () and high discharge efficiency (η) are beneficial to realize the device miniaturization, lightweight property, and sustainability of advanced pulse power systems. The obtainment of a high electric breakdown strength () is crucial for improving the energy storage performance of dielectric materials. However, as for BiNaTiO (BNT) lead-free relaxor ferroelectric ceramics, the relatively lower directly limits their electrical performance improvement and practical applications.

Solubilization techniques used for poorly water-soluble drugs.

About 40% of approved drugs and nearly 90% of drug candidates are poorly water-soluble drugs. Low solubility reduces the drugability. Effectively improving the solubility and bioavailability of poorly water-soluble drugs is a critical issue that needs to be urgently addressed in drug development and application.

Adaptive growth strategies of to drought and nitrogen enrichment: a physiological and biochemical perspective.

Nitrogen deposition and drought significantly influence plant growth and soil physicochemical properties. This study investigates the effects of nitrogen deposition and water stress on the growth and physiological responses of , and how these factors interact to influence the overall productivity. Two-year-old potted seedlings were selected to simulate nitrogen deposition and water stress.

Experimental study on the mechanical properties of C30 molybdenum tailings concrete after high-temperature and sulfate corrosion.

In order to study the durability of molybdenum tailings concrete after a specific period of wet-dry cycle tests and exposure to high temperatures, this paper investigates the rule of change of the mechanical properties of molybdenum tailings concrete under the coupled influence of sulfate corrosion and high-temperature environmental conditions. A total of five C30 concrete prisms with molybdenum tailings content (0 %, 25 %, 50 %, 75 %, and 100 %) were considered in the tests, with sulfate solution concentrations of 0 g/L, 20 g/L, and 50 g/L, and exposure temperatures of 25° at room temperature and 400° at high temperature, respectively. The test results showed that the mass loss rate of concrete prisms with different molybdenum tailings substitution rates under sulfate corrosion and high temperature environment showed an increasing and then decreasing trend.

[The influence of vowel and sound intensity on the results of voice acoustic formant detection was analyzed].

This study aims to explore the influence of vowels and sound intensity on formant, so as to provide reference for the selection of sound samples and vocal methods in acoustic detection. Thirty-eight healthy subjects, 19 male and 19 female, aged 19-24 years old were recruited. The formants of different vowels（/a/, //, /i/ and /u/） and different sound intensities（lowest sound, comfort sound, highest true sound and highest falsetto sound） were analyzed, and pairings were compared between groups with significant differences.

The dynamics and assembly patterns of airborne pathogen communities in the municipal food waste treatment system and its risk implications.

While municipal solid waste (MSW) provides an ideal habitat for pathogen propagation, the dynamics and assembly of airborne pathogen communities in these environments remain largely unknown. Here, we combined amplicon and metagenomics with spatiotemporal sampling to study inhalable particulate matter-carried potential pathogenic bacteria at full-scale food waste treatment plants (FWTPs), alongside comparisons to urban air in the area. The results showed that pathogenic bacteria constituted a notable portion (64.

MRI-Based Structural Failure Comparison between Chinese and American White Women With Prolapse: A Case-Control Study.

Introduction And Hypothesis: Although some evidence suggests that Chinese and white women might have different pelvic floor anatomy such as levator complex and connective tissue support for pelvic organs, it is unknown if these differences affect the mechanisms of pelvic organ prolapse. We sought to determine whether differences exist in MRI-based structural failure patterns between Chinese and American white women with prolapse.

Methods: This is a case-control study in different racial cohorts recruited in China and the USA.

Postharvest 24-epibrassinolide treatment improves chilling resistance of peach fruit via PpHDT1 modulating brassinosteroid metabolism.

Brassinosteroids (BRs) exhibit a positive effect on facilitating chilling resistance in fruits and vegetables. However, the change and regulatory mechanism of BR metabolism in fruits and vegetables are poorly understood. This study aimed to explore the underlying relationship among chilling injury (CI), BR metabolism and regulatory factor PpHDT1.

Hereditary vitreoretinal amyloidosis with transthyretin Gly83Arg variant, a long-term study.

Background: This study evaluated the clinical data on ophthalmic follow-up and treatment efficacy of hereditary vitreoretinal amyloidosis kindred due to transthyretin Gly83Arg variant over a 15-year follow-up period.

Methods: The clinical data of patients with hereditary ATTRG83R amyloidosis from 2006 to 2021 were analysed retrospectively. Sanger sequencing of the transthyretin gene, detailed medical history, pedigree charting, and systemic and ophthalmic examinations were carried out in all patients.

A novel pelvic magnetic resonance imaging measurement for pelvic organ prolapse evaluation.

Background: Pelvic magnetic resonance imaging has been proven effective for quantifying the extent of prolapse. The pubococcygeal line is used universally as a reference line in measuring pelvic organ prolapse; however, it focuses solely on 3 lowest points in the anterior, middle, and posterior pelvic compartments, without taking into account other pelvic floor structures and their interactions.

Objective: This study aimed to introduce and validate the area under the pubococcygeal line, a novel measurement method for evaluating pelvic organ prolapse, to examine its correlation with clinical Pelvic Organ Prolapse Quantification staging, and assess its reliability across different raters.